@article{oai:repo.qst.go.jp:00043853,
 author = {Noda, Shuhei and Iwakawa, Mayumi and Oota, Toshie and Iwata, Masaru and Yang, Minfu and Gotou, Miyako and Tanaka, Hiroko and Harada, Yoshinobu and Imai, Takashi and 野田 秀平 and 岩川 眞由美 and 太田 敏江 and 岩田 賢 and 中渡 美也子 and 田中 裕子 and 原田 良信 and 今井 高志},
 issue = {4},
 journal = {Cancer Detection and Prevention},
 month = {},
 note = {AIM: To gain insights into inter-strain differences in radiosensitivity. METHODS: Mice of inbred strains, A/J, C57BL/6J, and C3H/HeMs, were irradiated at graded doses ranging from 20 to 60 Gy. Skin reaction and leg contraction were observed for a period of 230 days and between 175 and 350 days, respectively. Gene expressions in leg skin tissue were quantified by quantitative RT-PCR assay at 1, 12 and 72 h after 30 Gy irradiation. Mice were locally irradiated by using a Cs-137 source. RESULTS: The three strains showed various degrees of susceptibility to irradiation has evaluated by skin scores. Large inter-strain differences were also detected in the lengths of contraction. Expressions of several genes such as Per3 and Rad51ap1 displayed inter-strain differences. CONCLUSIONS: The continuum model of tissue injury revealed that genetic factor, which varies among strains, is one of the causes of variances in severity of damage after irradiation.},
 pages = {376--382},
 title = {Inter-strain variance in late phase of erythematous reaction or leg contracture after local irradiation among three strains of mice},
 volume = {29},
 year = {2005}
}