{"created":"2023-05-15T14:33:47.746557+00:00","id":43840,"links":{},"metadata":{"_buckets":{"deposit":"76ba623a-4db0-4bef-9b16-29c853655d40"},"_deposit":{"created_by":1,"id":"43840","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"43840"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00043840","sets":["1"]},"author_link":["435876","435869","435856","435855","435862","435871","435858","435875","435872","435859","435866","435864","435874","435857","435868","435867","435863","435873","435861","435860","435870","435865"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"1244","bibliographicPageStart":"1237","bibliographicVolumeNumber":"63","bibliographic_titles":[{"bibliographic_title":"International Journal of Radiation Oncology Biology Physics"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose: To evaluate the potential importance of radioactive 9C-ion beam in cancer radiotherapy.    Methods and Materials: Human salivary gland (HSG) cells were exposed to a double-radiation-source 9C beam at different depths around the Bragg peak. Cell survival fraction was determined by standard clonogenic assay. For comparison, the same experiment was conducted for a therapeutic 12C beam. To determine relative biologic effectiveness (RBE) values, HSG cells were also irradiated with 60Co gamma-rays of fractionation scheme as the reference.    Results: The 9C beam was more efficient in cell killing at the depths around its Bragg peak than was the 12C beam, which corresponded to the 9C-ion stopping region and where delayed low-energy particles were emitted. The RBE value at 50% survival level for the 9C beam varied from 1.38 to 4.23. Compared with the 12C beam, the RBE values for the 9C beam were always higher; an increase in RBE by a factor of up to 1.87 has been observed at the depths distal to the Bragg peak.    Conclusion: The potential advantage of radioactive 9C-ion beam in cancer therapy has been revealed at low dose rate in comparison with a therapeutic 12C beam. This observation, however, remains to be investigated at therapeutic dose rates in the future.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0360-3016","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Li, Qiang"}],"nameIdentifiers":[{"nameIdentifier":"435855","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Furusawa, Yoshiya"}],"nameIdentifiers":[{"nameIdentifier":"435856","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanazawa, Mitsutaka"}],"nameIdentifiers":[{"nameIdentifier":"435857","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanai, Tatsuaki"}],"nameIdentifiers":[{"nameIdentifier":"435858","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kitagawa, Atsushi"}],"nameIdentifiers":[{"nameIdentifier":"435859","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aoki, Mizuho"}],"nameIdentifiers":[{"nameIdentifier":"435860","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Urakabe, Eriko"}],"nameIdentifiers":[{"nameIdentifier":"435861","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tomitani, Takehiro"}],"nameIdentifiers":[{"nameIdentifier":"435862","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Satou, Shinji"}],"nameIdentifiers":[{"nameIdentifier":"435863","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshimoto, Mitsuo"}],"nameIdentifiers":[{"nameIdentifier":"435864","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"zenkyuan, wei"}],"nameIdentifiers":[{"nameIdentifier":"435865","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"李 強","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435866","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古澤 佳也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435867","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"金澤 光隆","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435868","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"金井 達明","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435869","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"北川 敦志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435870","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"青木 瑞穂","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435871","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"新谷 恵理子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435872","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"富谷 武浩","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435873","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤 眞二","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435874","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"吉本 光男","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435875","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"衛 増泉","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"435876","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Enhanced efficiency in cell killing at the penetration depths around the Bragg peak of a radioactive 9C-ion beam","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Enhanced efficiency in cell killing at the penetration depths around the Bragg peak of a radioactive 9C-ion beam"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2005-11-04"},"publish_date":"2005-11-04","publish_status":"0","recid":"43840","relation_version_is_last":true,"title":["Enhanced efficiency in cell killing at the penetration depths around the Bragg peak of a radioactive 9C-ion beam"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:22:26.981608+00:00"}