@article{oai:repo.qst.go.jp:00043763,
 author = {Tsuji, Atsushi and Sugyou, Aya and Ogiu, Toshiaki and Sagara, Masashi and Suga, Tomo and Ishikawa, Atsuko and Sudou, Hitomi and Ohtuki, Marika and Aburatani, Hiroyuki and Imai, Takashi and Harada, Yoshinobu and 辻 厚至 and 須尭 綾 and 荻生 俊昭 and 相良 雅史 and 菅 智 and 石川 敦子 and 須藤 仁美 and 大月 まり香 and 今井 高志 and 原田 良信},
 journal = {Genomics},
 month = {Sep},
 note = {LEC rats constitute an animal model of high susceptibility to X-rays. We developed congenic LEC rat lines (recipient strain, Fischer 344 (F344)) and performed genome-wide genotyping to identify radiation susceptibility genes. We mapped seven positional candidate genes, Bmp10, Gpr73, Gp9, Cnbp, Copg, Rab7, and Rpn1, to an approximately 1.2-Mb region located between loci D4Got85 and D4Got148 on chromosome 4. None of the seven genes has been reported to be associated with radiation susceptibility. Comparison of the coding sequences for these seven genes in F344 and LEC rats showed no changes in deduced amino acid sequences. We determined gene expression differences in Gp73, Gp9, and Cnbp as well as strain-specific variations in upstream sequences of these genes. Our results suggest that radiation susceptibility in the LEC rat is primarily attributable to one of the genes within this approximately 1.2-Mb region; however, expression analysis gave no clear indication as to which gene is responsible.},
 pages = {271--279},
 title = {Fine Mapping of Radiation Susceptibility and Gene Expression Analysis of LEC Congenic Rat Lines},
 volume = {86},
 year = {2005}
}