@article{oai:repo.qst.go.jp:00043739,
 author = {Watanabe, Naoyuki and Tanada, Shuji and Sasaki, Yasuhito and 渡辺 直行 and 棚田 修二 and 佐々木 康人},
 issue = {4},
 journal = {Radiation Protection Dosimetry},
 month = {May},
 note = {The efficacy of diethylenetriaminepentaacetate calcium trisodium (CaNa3DTPA) in a dese of 34.7  mol kg-1 as a function of its route of administration was investigated in rats with a puncture wound contaminated by 90Y-chloride at a concentration of 2.55 MBq kg-1. Approximately 60% of 90Y-chloride at a puncture wound was absorbed into the body of rats over 72 h post-puncture and radioactivity in gemoral bone increased during the timed-release of 90Y. Intravenous administration of CaNaDTPA (systemic treatment) at 15 min post-puncture reduced 90Y at a puncture wound and in bone up to 75.6 and 84.3% of controls, respectively. Direct infiltration of CaNaDTPA into a puncture wound site (local treatment) at 15 min post-punctre diminished radioactivity at the puncture wound and in bone up to 34.9 and 52.5% of controls, respectively.
Thus, prompt local treatment may be effective for removing 90Y from a puncture wound and minimising 90Y-distribution to bone compared with systemic treatment.},
 pages = {509--513},
 title = {EFFECT OF CALCIUM TRISODIUM DTPA IN RATS WITH PUNCTURE WOUND CONTAMINATED BY 90Y-CHLORIDE},
 volume = {114},
 year = {2005}
}