{"created":"2023-05-15T14:33:38.608313+00:00","id":43641,"links":{},"metadata":{"_buckets":{"deposit":"ffb4e88c-0bd0-4ca9-b19a-da0e3be06f2c"},"_deposit":{"created_by":1,"id":"43641","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"43641"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00043641","sets":["1"]},"author_link":["433913","433916","433911","433910","433920","433912","433914","433917","433918","433915","433907","433908","433909","433919"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"383","bibliographicPageStart":"375","bibliographicVolumeNumber":"43","bibliographic_titles":[{"bibliographic_title":"Journal of Labelled Compounds & Radiopharmaceuticals"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Derivatives of 9,10-ethanobenzo[b]quinolizinium are potent antagonists of the TCP-site of the NMDA receptor. Two fluoroethyl-substituted analogues were labelled with fluorine-18 by displacement of the tosylate with [18F]fluoride, followed by a Diels-Alder reaction. A methoxy-substituted analogue labelled with carbon-11 was obtained by O-methylation of the corresponding hydroxy precursor with [11C]iodomethane. In biodistribution studies in mice with these three radioligands, it was found that they have little ability to penetrate the blood-brain barrier.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0362-4803","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ishibashi, Nobuyasu"}],"nameIdentifiers":[{"nameIdentifier":"433907","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kuwamura, T"}],"nameIdentifiers":[{"nameIdentifier":"433908","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sano, H"}],"nameIdentifiers":[{"nameIdentifier":"433909","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamamoto, Fumihiko"}],"nameIdentifiers":[{"nameIdentifier":"433910","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Haradahira, Terushi"}],"nameIdentifiers":[{"nameIdentifier":"433911","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Kazutoshi"}],"nameIdentifiers":[{"nameIdentifier":"433912","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suhara, Tetsuya"}],"nameIdentifiers":[{"nameIdentifier":"433913","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sasaki, Shigeki"}],"nameIdentifiers":[{"nameIdentifier":"433914","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Maeda, Minoru"}],"nameIdentifiers":[{"nameIdentifier":"433915","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"原田平 輝志","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433916","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木 和年","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433917","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"須原 哲也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433918","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐々木 茂貴","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433919","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"前田 稔","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433920","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Synthesis and Evaluation of 18F-and 11C-Labelled 9,10-Ethanobenzo[b]quinolizinium Derivatives for Imaging of the NMDA Receptor at the TCP-Binding Site","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Synthesis and Evaluation of 18F-and 11C-Labelled 9,10-Ethanobenzo[b]quinolizinium Derivatives for Imaging of the NMDA Receptor at the TCP-Binding Site"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2005-03-02"},"publish_date":"2005-03-02","publish_status":"0","recid":"43641","relation_version_is_last":true,"title":["Synthesis and Evaluation of 18F-and 11C-Labelled 9,10-Ethanobenzo[b]quinolizinium Derivatives for Imaging of the NMDA Receptor at the TCP-Binding Site"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:24:48.536971+00:00"}