{"created":"2023-05-15T14:33:35.292248+00:00","id":43567,"links":{},"metadata":{"_buckets":{"deposit":"c0647d9d-9716-4a27-8f04-2023f92c5e1e"},"_deposit":{"created_by":1,"id":"43567","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"43567"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00043567","sets":["1"]},"author_link":["433177","433178","433179","433176"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"102","bibliographicPageStart":"93","bibliographicVolumeNumber":"16","bibliographic_titles":[{"bibliographic_title":"Journal of Toxicologic Pathology"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Lymphoid neoplasms occurring in three different (C3H/He, C57BL/6, and B6C3F1) strains of female mice after injection of the bone-seeking and alpha-emitting radionuclide, 239Pu citrate were compared by immunohistochemistry with those from the alkylating agent, N-methyl-N-nitrosourea (MNU)-injected mice.  There was a variety of phenotypes from either T-cell to B-cell or histiocytic lineages in lymphoid neoplasms of the control, saline-injected mice.  While strain differences were noted in the incidence and proportion, lymphoid neoplasms occurring early after 239Pu-injection were, however, characterized by B220+ phenotypes but negative for both T-cell-specific markers (Thy1, CD3) and B-cell markers (CD5, CD19, CD79b) to be classified into pre-B-cell lymphomas derived from progenitor B-cells.  In contrast, almost all the MNU-induced lymphomas were shown to be CD3+ or rarely Thy1+ but B220- T-lymphoblastic lymphomas.  These results indicate differences in immunophenotypic expression but also might reflect different carcinogenic processes between chemical- and radiation-induced murine lymphomas.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0914-9198","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Oghiso, Yoichi"}],"nameIdentifiers":[{"nameIdentifier":"433176","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Yutaka"}],"nameIdentifiers":[{"nameIdentifier":"433177","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小木曽 洋一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433178","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山田 裕","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"433179","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Pre-B-Cell Lymphomas in Mice Following Injection of 239Pu Citrate: Comparison with MNU-Induced T-Lymphoblastic Lymphomas","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Pre-B-Cell Lymphomas in Mice Following Injection of 239Pu Citrate: Comparison with MNU-Induced T-Lymphoblastic Lymphomas"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2004-12-15"},"publish_date":"2004-12-15","publish_status":"0","recid":"43567","relation_version_is_last":true,"title":["Pre-B-Cell Lymphomas in Mice Following Injection of 239Pu Citrate: Comparison with MNU-Induced T-Lymphoblastic Lymphomas"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:25:41.773294+00:00"}