@article{oai:repo.qst.go.jp:00043559, author = {Yoshimoto, Yasuhiko and Yoshinaga, Shinji and Yamamoto, Kazuhide and Fujimoto, Kenzo and Nishizawa, Kanae and Sasaki, Yasuhito and 吉本 泰彦 and 吉永 信治 and 山本 一英 and 藤元 憲三 and 西澤 かな枝 and 佐々木 康人}, issue = {4}, journal = {Journal of Radiological Protection}, month = {Dec}, note = {The results of a geographical correlation study using Poisson regression analysis are reported for leukaemia and malignant lymphoma mortality between 1972 and 1997 in 100 selected Japanese municipalities with or without a nuclear power plant (NPP). The data did not support social concerns of an increased risk of malignant lymphoma in vicinity of Japanese NPPs. However, some estimates of overall excess relative risk (ERR; relativer risk minus one) were statistically significantly positive for leukemia mortality in 20 NPP municipalities compared with mortality in the remaining 80 control areas, taking into account a minimum two-year latency following the start of commercial operation. One estimate was 0.228 (95% CI: 0.074-0.404) from a simple area adjustment using the mortality in all Japan as the external baseline rate. This superficial increase is not due to leukaemia among young people, aged less than 25 years at death. The ERR estimate for ages at death of 50-74 years was confounded to be positive for leukemia and distorted to be negative for malignant lymphoma. For leukemia, a positive ERR estimate was seen, especially for females and during specific periods. Confounding of the ERR estimate for two causes was also seen in some NPP areas including a high adult T-cell leukemia (ATL) area. Temporal area variations associated with ATL misclassification and a temporal increasing trend of leukaemia mortality in the elderly caused the confounding effects. Our findings do not support the hypothesis of a leukaemogenic impact of NPPs in Japan.}, pages = {343--368}, title = {Research on potential radiation risks in areas with nuclear power plants in Japan: leukaemia and malignant lymphoma mortality between 1972 and 1997 in 100 selected municipalities}, volume = {24}, year = {2004} }