{"created":"2023-05-15T14:33:33.721180+00:00","id":43532,"links":{},"metadata":{"_buckets":{"deposit":"b9baad07-436d-40b8-971e-a811221a57c4"},"_deposit":{"created_by":1,"id":"43532","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"43532"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00043532","sets":["1"]},"author_link":["432911","432913","432915","432910","432912","432914"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"584","bibliographicPageStart":"580","bibliographicVolumeNumber":"162","bibliographic_titles":[{"bibliographic_title":"Radiation Research"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Pregnant females of C57BL/10JHir mice at 9 days of gestation were whole-body irradiated with a single acute dose of carbon ion-radiations. Average linear energy transfer (LET) of carbon ion-radiations was 50 keV/um within a spread-out-Bragg-peak (SOBP). The effect was studied by scoring changes in the postnatal development of mice as well as in the pigmentation of cutaneous coats and tail-tips of offspring 22 days after birth. The percentage of birth was reduced in mice exposed to carbon ion-radiations at doses greater than 0.5 Gy. The survival to day 22 was also reduced in mice exposed to carbon ion-radiations at doses greater than 0.75 Gy. Moreover, the body weight at day 22 was reduced in mice exposed to carbon ion-radiations at doses greater than 0.1 Gy. By comparing the survival to day 22 for carbon ion-radiations with that of our previous data of 60Co-g-rays, carbon ion-radiations were twice as effective as g-rays. White spots were found in the mid-ventrum as well as in the tail-tips of offspring exposed to carbon ion-radiations. The frequency and the size of the white spots in the mid-ventrum as well as in the tail-tips increased as the dose increased. Carbon ion-radiations seem to be slightly more effective than g-rays reported in our previous paper. In the ventral white spots, no melanocytes were observed in the epidermis, dermis and hair follicles. These results indicate that prenatal carbon-ion radiations have a greater effect on postnatal development and survival of mice than do g-rays; and that the relative biological effectiveness is greater than that for effects on melanocyte development.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0033-7587","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hirobe, Tomohisa"}],"nameIdentifiers":[{"nameIdentifier":"432910","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Eguchi-Kasai, Kiyomi"}],"nameIdentifiers":[{"nameIdentifier":"432911","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Murakami, Masahiro"}],"nameIdentifiers":[{"nameIdentifier":"432912","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"廣部 知久","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"432913","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"笠井 清美","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"432914","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"村上 正弘","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"432915","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of Carbon-Ion Radiation on the Postnatal Development of Mice and on the Yield of White Spots in the Mid-Ventrum and Tail Tips","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of Carbon-Ion Radiation on the Postnatal Development of Mice and on the Yield of White Spots in the Mid-Ventrum and Tail Tips"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2004-11-05"},"publish_date":"2004-11-05","publish_status":"0","recid":"43532","relation_version_is_last":true,"title":["Effects of Carbon-Ion Radiation on the Postnatal Development of Mice and on the Yield of White Spots in the Mid-Ventrum and Tail Tips"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:26:09.731884+00:00"}