@article{oai:repo.qst.go.jp:00043448,
 author = {Kage, Takahiro and Takeda, Hiroyuki and Yasuda, Takako and Maruyama, Kouichi and Yamamoto, Naoyuki and Yoshimoto, Masami and Araki, Kazuo and Inohaya, Keiji and Okamoto, Hiroyuki and Yasumasu, Shigeki and Watanabe, Kaori and Itou, Hironobu and Ishikawa, Yuuji and 景 崇洋 and 丸山 耕一 and 安増 茂樹 and 舘野 香里 and 石川 裕二},
 journal = {The Journal of Comparative Neurology},
 month = {},
 note = {We examined the morphogenesis and regionalization of the embryonic brain of an acanthopterygian teleost,medaka(Oryzias latipes), by in situ hybridization using 14 gene probes. We compared our results with previous studies in other vertebrates, particularly zebrafish, an ostariophysan teleost.
 During the early development of the medaka neural rod, three initial brain vesicles arose: the anterior brain vesicle, which later developed into the telencephalon and rostral diencephalon; the intermediate brain vesicle, which later developed into the caudal diencephalon,mesencephalon and metencephalon; and the posterior brain vesicle, which later developed into the myelencephalon. In the late neural rod, the rostral brain bent ventrally and the axis of the brain had a marked curvature at the diencephalon. In the final stage of the neural rod, ventricles began to develop,transforming the neural rod into the neural tube. In situ hybridization revealed that the brain can be divided into three longitudinal zones (dorsal, intermediate and ventral) and many transverse subdivisions, on the basis of molecular expression patterns. The telencephelon was subdivided into two transverse domains. Our results support the basic concept of neuromeric models, including the prosomeric model, which suggest the existence of a conserved organization of all vertebrate neural tubes. Our results also show that brain development in medaka differs from that reported in other vertebrates, including zebrafish, in gene-expression patterns in the telencephalon, in brain vesicle formation and in developmental speed. Developmental and genetic programs for brain development may be somewhat different even among teleosts.},
 pages = {219--239},
 title = {Morphogenesis and regionalization of the medaka embryonic brain},
 volume = {476},
 year = {2004}
}