@article{oai:repo.qst.go.jp:00043325,
 author = {Matsumura, Satoko and Matsumura, Tatsushi and Ozeki, Shuuji and Fukushima, Shoko and Yamazaki, Hideya and Inoue, Takehiro and Inoue, Toshihiko and Furusawa, Yoshiya and Eguchi-Kasai, Kiyomi and 松村 聡子 and 大関 修治 and 山崎 秀哉 and 井上 武宏 and 井上 俊彦 and 古澤 佳也 and 笠井 清美},
 journal = {Cancer Detection and Prevention},
 month = {Mar},
 note = {Heavy-ion beams are more effective than gamma-rays in causing G2 arrest. In this study, we investigated the expression of Wee1 and Cdc2 protein levels in order to analyze the G2 arrest caused by carbon-ion beam irradiation. Human lymphoblastoid TK6 cells were exposed to a 75 keV carbon-ion beam or 137Cs gamma-rays. Although the levels of Wee1 and Cdc2 protein were increased after exposure to either beam, Wee1 protein levels were influenced more by carbon-ion beam irradiation than by gamma-rays. To the contrary, Cdc2 protein levels were increased more by gamma-rays than by carbon-ion beams. These findings suggest that the G2 arrest produced by heavy-ion beams, such as the carbon-ion irradiation used in this study, might be associated with the overexpression of the Wee1 protein and of Cdc2 phosphorylation regulated by Wee1. Together, these events may act to prolong the length of G2 arrest.},
 pages = {222--228},
 title = {Comparative analysis of G2 arrest after irradiation with 75 keV carbon-ion beams and 137Cs gamma-rays in a human lymphoblastoid cell line.},
 volume = {27},
 year = {2003}
}