@article{oai:repo.qst.go.jp:00043283,
 author = {Yoshida, Kazuko and Aizawa, Shirou and Watanabe, Keiko and Hirabayashi, Yoko and Inoue, Tohoru and 吉田 和子 and 相澤 志郎 and 渡辺 恵子 and 平林 容子 and 井上 達},
 journal = {Leukemia Research},
 month = {},
 note = {C3H/He mice produce myeloid leukemias after whole body irradiation of 1-3Gy as compared with non-irradiated controls that produce fewer than 1% of leukemia [Radiation Research 127 (1991) 146]. Thus, p53-deficient C57BL/6 strain, a malignant lymphoma prone, was crossed back into C3H/He strain. Lethally irradiated wild-type mice to which p53-deficient bone marrow cells were transplanted (transplantation assay) showed dramatic change in the propensity of leukemia of myeloid lineages, the cells lacking CD3, Thy1.2, sIgM, B220, Mac-1, Gr-1, but being positive for c-Kit and CD44. Furthermore, transplanted mice subjected to 3Gy irradiation gave rise to a faster development of leukemia and a higher frequency of double-lineage leukemias than the non-irradiated control.},
 pages = {1085--1092},
 title = {Stem-cell leukemia: p53 deficiency mediated suppresion of leukemic differentiation in C3H/He myeloid leukemia},
 volume = {26},
 year = {2002}
}