{"created":"2023-05-15T14:33:20.280371+00:00","id":43231,"links":{},"metadata":{"_buckets":{"deposit":"b0aa927e-10d8-4804-98cb-65c7ace9209b"},"_deposit":{"created_by":1,"id":"43231","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"43231"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00043231","sets":["1"]},"author_link":["430070","430072","430068","430069","430071"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-10","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"161","bibliographicPageStart":"158","bibliographicVolumeNumber":"37","bibliographic_titles":[{"bibliographic_title":"Japanese Journal of Health Physics"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The effects of a daily recommended human dose (1 g per 70 kg body weight=30 mmol/kg) of calcium diethylentriaminepentaacetic acid (Ca-DTPA) on removal of plutonium from rats injected with different amounts of plutonium were examined. Sixty female wistar rats were preinjected with doses of 0.185, 0.37 and 3.7 x105 Bq/kg of plutonium as a nitrate, and half of the rats of each dose group were injected with 30 mmol/kg of Ca-DTPA for 3 days, beginning 1 h after plutonium injection on the first day. The 24-h urine and feces of rats were collected. The amount of urinary plutonium excretion in the Ca-DTPA groups was found to be significantly greater than that in the respective corresponding control groups at day 1-3. The amount of urinary plutonium excretion in the Ca-DTPA group at the 1st day was increased in response to the plutonium injected dose (correlation coefficient: r=0.628, vs. r=0.573 in the control group), that accumulated in the Ca-DTPA group for 3 days was r=0.800 vs. r=0.669 in the control group), while their rates of plutonium injected dose were decreased. Such findings were not obtained in the feces measurements. In conclusion, a human dose of Ca-DTPA chelation therapy enhances plutonium excretion as increasing plutonium intake, however the excreted rate of plutonium intake is decreased.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0367-6110","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fukuda, Satoshi"}],"nameIdentifiers":[{"nameIdentifier":"430068","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yan, Xueming"}],"nameIdentifiers":[{"nameIdentifier":"430069","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Iida, Haruzo"}],"nameIdentifiers":[{"nameIdentifier":"430070","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福田 俊","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"430071","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"飯田 治三","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"430072","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of a human dose of Ca-DTPA on removal of plutonium in rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of a human dose of Ca-DTPA on removal of plutonium in rats"}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2003-11-05"},"publish_date":"2003-11-05","publish_status":"0","recid":"43231","relation_version_is_last":true,"title":["Effects of a human dose of Ca-DTPA on removal of plutonium in rats"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:29:44.896939+00:00"}