@article{oai:repo.qst.go.jp:00043124,
 author = {Yamada, Shigeru and Durante, Marco and Ando, Koichi and Furusawa, Yoshiya and Kawata, Tetsuya and Majima, Hideyuki and Tsujii, Hirohiko and 山田 滋 and 安藤 興一 and 古澤 佳也 and 馬嶋 秀行 and 辻井 博彦},
 journal = {Cancer Letters},
 month = {},
 note = {The new methods of chemical-induced premature chromosome condensation combined with fluorescence in situ hybridization was used to analyze chromosomal damage in peripheral blood mononuclear lymphocytes of patients undergoing radiation treatment for esophageal cancer with high-energy X-rays or accelerated carbon ions at the National Institute of Radiological Sciences(Chiba, Japan). Total number of aberrant cells correlated with radiation field size, but no correlation was found with acute toxity. A high frequency of complex-type exchanges were also recorded. This aberration type presented a high individual variability, and correlated well with the acute morbidity. Cytogenetic analysis by interphase chromosome painting is proposed as a useful tool for monitoring normal tissue effects during radiotherapy.},
 pages = {215--221},
 title = {Complex-type chromosomal exchanges in blood lymphocytes during radiation therapy correlate with acute toxicity},
 volume = {150},
 year = {2000}
}