@article{oai:repo.qst.go.jp:00043096, author = {Matsufuji, Naruhiro and Fukumura, Akifumi and Komori, Masataka and Kanai, Tatsuaki and Kohno, Toshiyuki and 松藤 成弘 and 福村 明史 and 小森 雅孝 and 金井 達明 and 河野 俊之}, journal = {Physics in Medicine and Biology}, month = {Jun}, note = {The production of projectile fragments is one of the important, but not yet perfectly understood, problems to be considered when planning for the utilization of high-energy heavy charged particles for radiotherapy. This paper reports our investigation of the fragments' fluence and LET spectra produced from various incident ions using an experimental approach to reveal these physical qualities of the beams. PMMA (Polymethyl Methacrylate), as a substitute for the human body, was used as a target. A DeltaE-E counter telescope with a plastic scintillator and a BGO scintillator made it possible to identify the species of fragments based on differences of various elements. By combining a gas-flow proportional counter with a counter telescope system, LET spectra as well as fluence spectra of the fragments were derived on each element down from the primary particles to hydrogen. Among them, the information on hydrogen and helium fragments was derived for the first time. The result revealed that the number of light fragments, such as hydrogen and helium, became larger than that the number of primaries in the vicinity of the range end. However, the greater part of the dose delivered to a cell was still governed by the primaries. The calculated result of a simulation used for heavy-ion radiotherapy indicated room for improving the reaction model.}, pages = {1605--1623}, title = {Influence of fragment reaction of relativistic heavy charged particles on heavy-ion radiotherapy}, volume = {48}, year = {2003} }