{"created":"2023-05-15T14:33:04.618585+00:00","id":42883,"links":{},"metadata":{"_buckets":{"deposit":"87858223-3a97-46ce-8d4e-4ff0302d8206"},"_deposit":{"created_by":1,"id":"42883","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"42883"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00042883","sets":["1"]},"author_link":["426848","426846","426850","426851","426847","426852","426849"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-04","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"38","bibliographicPageStart":"32","bibliographicVolumeNumber":"19","bibliographic_titles":[{"bibliographic_title":"Journal of Mammalian Ova Research"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In vitro fertilizability and subsequent developmental competence of inbred RFM/Ms mice, which have high incidence of myeloid leukemia by radiation, was studied. When response of RFM/Ms females to various amount of eCG (1.25-10.0 i.u.) was examined, superovulation (>20 ovulated ova) occurred in animals injected with ³5.0 i.u. eCG. The kinetics of in vitro fertilization and embryo development were examined and compared among RFM/Ms, C57BL/6J zygotes and their hybrid zygotes. The fertilization kinetics was significantly slower in RFM/Ms zygotes than in C57BL/6J zygotes. Crossbreeding experiments between C57BL/6J and RFM/Ms showed that the speed and incidence of fertilization were affected by paternal and maternal factors, respectively. The in vitro development to the blastocyst stage of RFM/Ms zygotes was significantly slower than that of C57BL/6J zygotes and their hybrid zygotes at 96h post-insemination (PI), but not at 120h PI. The nuclear number of RFM/Ms embryos was significantly lower than that of C57BL/6J and their hybrid embryos throughout the culture period (72, 96 and 120h PI). Conversely, hatching at 120h PI in C57BL/6J embryos was much slower than that of the other groups of embryos. This study showed that gametes and zygotes of RFM/Ms strain can be fertilized and developed well in vitro and that maternal and paternal factors and their interaction have complicated effects on fertilization and developmental kinetics in vitro.","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-7738","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kito, Seiji"}],"nameIdentifiers":[{"nameIdentifier":"426846","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tateno, Shintarou"}],"nameIdentifiers":[{"nameIdentifier":"426847","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Oota, Yuki"}],"nameIdentifiers":[{"nameIdentifier":"426848","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Noguchi, Yoshiko"}],"nameIdentifiers":[{"nameIdentifier":"426849","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鬼頭 靖司","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"426850","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"舘野 真太郎","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"426851","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"太田 有紀","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"426852","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Kinetics of in vitro fertilization and development of an inbred mouse strain: study using RFM/Ms compared with C57BL/6J.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Kinetics of in vitro fertilization and development of an inbred mouse strain: study using RFM/Ms compared with C57BL/6J."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2002-05-31"},"publish_date":"2002-05-31","publish_status":"0","recid":"42883","relation_version_is_last":true,"title":["Kinetics of in vitro fertilization and development of an inbred mouse strain: study using RFM/Ms compared with C57BL/6J."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:33:48.908048+00:00"}