{"created":"2023-05-15T14:33:04.003600+00:00","id":42869,"links":{},"metadata":{"_buckets":{"deposit":"4bec91ef-ad4d-4845-b5ee-999a8a58e143"},"_deposit":{"created_by":1,"id":"42869","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"42869"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00042869","sets":["1"]},"author_link":["426693","426690","426692","426691","426696","426694","426697","426685","426687","426695","426686","426689","426688"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2001","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"391","bibliographicPageStart":"383","bibliographicVolumeNumber":"27","bibliographic_titles":[{"bibliographic_title":"Advances in Space Research"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We report measurements of initial G2-chromatid breaks in normal human fibroblasts exposed to various types of high-LET particles. Exponentially growing AG 1522 cells were exposed to gamma-rays or heavy ions. Chromosomes were prematurely condensed by calyculin A. Chromatid-type breaks and isochromatid-type breaks were scored separately. The dose response curves for the induction of total chromatid breaks (chromatid-type + isochromatid-type) and chromatid-type breaks were linear for each type of radiation. However, dose response curves for the induction of isochromatid-type breaks were linear for high-LET radiations and linear-quadratic for gamma-rays. Relative biological effectiveness (RBE), calculated from total breaks, showed a LET dependent tendency with a peak at 55 keV/um silicon (2.7) or 80 keV/um carbon (2.7) and then decreased with LET (1.5 at 440 keV/um). RBE for chromatid-type break peaked at 55 keV/um (2.4) then decreased rapidly with LET. The RBE of 440 keV/um iron particles was 0.7. The RBE calculated from induction of isochromatid-type breaks was much higher for high-LET radiations. It is concluded that the increased production of isochromatid-type breaks, induced by the densely ionizing track structure, is a signature of high-LET radiation exposure. ","subitem_description_type":"Abstract"}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0273-1177","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kawata, Tetsuya"}],"nameIdentifiers":[{"nameIdentifier":"426685","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Durante, Marco"}],"nameIdentifiers":[{"nameIdentifier":"426686","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Furusawa, Yoshiya"}],"nameIdentifiers":[{"nameIdentifier":"426687","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"George, Kerry"}],"nameIdentifiers":[{"nameIdentifier":"426688","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ito, Hisao"}],"nameIdentifiers":[{"nameIdentifier":"426689","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Wu, Honglu"}],"nameIdentifiers":[{"nameIdentifier":"426690","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"A, Cucinotta Francesca"}],"nameIdentifiers":[{"nameIdentifier":"426691","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"川田 哲也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"426692","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古澤 佳也","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"426693","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ジョージ ケリー","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"426694","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊東 久夫","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"426695","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ウー ホングル","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"426696","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"クシノッタ フランク","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"426697","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"G2-Chromosome Aberarions Induced by High-LET Radiations.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"G2-Chromosome Aberarions Induced by High-LET Radiations."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2002-02-12"},"publish_date":"2002-02-12","publish_status":"0","recid":"42869","relation_version_is_last":true,"title":["G2-Chromosome Aberarions Induced by High-LET Radiations."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:33:58.744319+00:00"}