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内容記述 |
Gadolinium (Gd)-based contrast agents used in MRI investigations are structured with strong chelate bonds to ensure safety from human administration to excretion. On the other hand, this Gd contrast agent is widely discharged into the environment after MRI investigations. After passing through sewage treatment facilities and being discharged into the environment, it denatures as highly toxic Gd3+ ions, which accumulate in aquatic organisms and have a high potential to affect biological life. This anthropogenic Gd was first observed in a German river in 1996, suggesting that the main component was derived from MRI contrast media. However, acceptable concentration levels of Gd in aqueous media have not been established, raising concerns about future environmental contamination.We would like to propose a novel method to introduce chelating groups onto conventional polymeric materials. As one of the methods to remove Gd contract agent derivatives from water body, we examined an adsorbent material with iminodiacetic acid groups introduced by radiation-induced graft polymerization (RIGP). RIGP has the advantage that general-purpose polymer materials with various shapes and properties can be freely selected, and desired functions can be introduced at high density. In this study, we report on the evaluation of the stability of Gd contrast agents and the characterization of Gd-adsorbent that can adsorb Gd, aiming at the establishment of a Gd removal technique form the environment. |
