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Detection of trace elements in bone tissues by high energy synchrotron radiation X-ray fluorescence analysis

https://repo.qst.go.jp/records/2002005
https://repo.qst.go.jp/records/2002005
5239c605-c2ef-4c82-b483-cfd6c8a5716d
アイテムタイプ 会議発表論文 / Conference Paper(1)
公開日 2026-01-09
タイトル
タイトル Detection of trace elements in bone tissues by high energy synchrotron radiation X-ray fluorescence analysis
言語 en
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言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_5794
資源タイプ conference paper
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アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Miyu Terauchi

× Miyu Terauchi

Miyu Terauchi

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Yakumaru Haruko

× Yakumaru Haruko

Yakumaru Haruko

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Ayama Kyoko

× Ayama Kyoko

Ayama Kyoko

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Chiya Numako

× Chiya Numako

Chiya Numako

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Takeda Shino

× Takeda Shino

Takeda Shino

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内容記述タイプ Abstract
内容記述 【High-energy synchrotron radiation X-ray fluorescence analysis with microbeam (SR-µXRF) is excellent for the detection of heavy metals and provides elemental imaging corresponding to the tissue microstructure, so we have been working on trace element analysis of bone tissue. In the case of bone tissue, there is a possibility that the quantitative evaluation of trace elements may include additive values from high matrix elements such as calcium and phosphorus. In this study, we prepared analytical standards[1] for quantitative analysis of iron and zinc in rat femur and investigated the effect of matrix on quantitative evaluation. The calibration curves obtained from the analytical standards showed high linearity, and the limits of quantification for iron and zinc were 1.66 μg/g and 0.56 μg/g at 10-second counting. The detection of zinc in bone tissue was not enhanced by the high-matrix component. For iron, the addition of high-matrix components was 2.29 ± 3.24% in the range of 5-500 μg/g, and the maximum addition was about 7%. These trace elements were not significantly affected by high matrix in this method. Elemental images in rat femur are also reported.References:[1] Y. Kato et al., Microchem. J. 207 (2024) 112278.
書誌情報 Metallomics Research

巻 5, 号 Suppl, p. 41, 発行日 2025-12
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