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Quantum Beam-Based Elemental Analysis for Biological Trace Element Research

https://repo.qst.go.jp/records/2002004
https://repo.qst.go.jp/records/2002004
e17371eb-7039-44e6-90f1-c7a01359f6ef
アイテムタイプ 会議発表論文 / Conference Paper(1)
公開日 2026-01-09
タイトル
タイトル Quantum Beam-Based Elemental Analysis for Biological Trace Element Research
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_5794
資源タイプ conference paper
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アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Takeda Shino

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Takeda Shino

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内容記述タイプ Abstract
内容記述 Chemical information of tissue and cellular elements, such as elemental distribution, localization, composition, and chemical status, is required for understanding biological trace elements. Quantum beam-based elemental analyses, such as particle induced X-ray emission (μPIXE) and synchrotron radiation X-ray fluorescence (SR-μXRF) analysis with microprobe, are promising research tactics for such purposes. μPIXE is excellent for detecting light elements, and imaging of biomatrix elements such as sulfur and phosphorus enables us to obtain the distribution and localization of target elements corresponding to the cell structure [1]. Synchrotron radiation X-ray fluorescence analysis (SR-XRF) is a special analysis at large synchrotron radiation facilities, but by using high-energy excitation X-rays, it is possible to detect heavy metals (tin, uranium, cesium, cadmium, etc.) at trace levels in tissues [2-4]. By combining PIXE and SR-XRF, element distribution dynamics from light to heavy elements can also be investigated [3, 4]. Furthermore, combining elemental imaging with X-ray absorption fine structure (XAFS) provides information on the chemical form of the localized elements in the tissues [3]. Application to blood and urine droplet specimens is also expected for contamination monitoring and medical applications. This symposium will present examples of these analyses.References:[1] Shino Homma-Takeda et al., Minerals 2021; 11: 191.[2] Shino Homma-Takeda et al., Nucl. Intr. Meth. Phys. Res. B 2005; 231: 333-337.[3] Shino Homma-Takeda et al., Int. J. Mol. Sci. 2019; 20: 4677-4687.[4] Haruko Yakumaru et al., Eur. Phys. J. Plus (in press).
書誌情報 Metallomics Research

巻 5, 号 Suppl, p. 8, 発行日 2025-12
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