| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-10-23 |
| タイトル |
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タイトル |
Effects of reflectors on the imaging performance of a mouse brain PET scanner with staggered 3-layer DOI detectors |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Hangyu Kang
Tashima Hideaki
Akamatsu Go
Yamaya Taiga
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background: For mouse brain positron emission tomography (PET), good spatial resolution and depth-of-interaction (DOI) information are necessary. Spatial and DOI resolutions of PET systems are highly affected by reflector materials. Nevertheless, the effects of reflector materials on the imaging performance have not been investigated in PET system levels.Purpose: Here, we systematically investigate the effects of reflector materials on the imaging performance of a mouse brain PET scanner using staggered 3-layer DOI detectors. Methods: We separately constructed mouse brain PET scanners with two reflector materials of barium sulfate (BaSO4) powder and enhanced specular reflector (ESR) film. The PET inner diameter (53 mm), crystal pitch (1 mm) and crystal layer thickness (4/4/7 mm) were the same for BaSO4 and ESR. Physical and imaging performance of the PET scanners were evaluated with the same silicon photomultipliers, and front-end electronics.4.Results: The system coincidence timing resolution with ESR (3.6 ns) was twice as good as that with BaSO4. (7.0 ns). However, the average radial resolution with BaSO4 (0.96 mm) was 0.2 mm better than that with ESR (1.16 mm) because of the reduced crystal decoding error. A narrow energy window (440-560 keV) effectively improved the valley-to-peak ratio of submillimeter rod structures especially for BaSO4 due to the reduced inter crystal scattering events, although at the expense of sensitivity. Conclusions: We found BaSO4 provided better spatial resolution and imaging performance over ESR for the mouse brain PET scanner with staggered 3-layer DOI detectors. |
| 書誌情報 |
Medical Physics
巻 52,
号 11,
発行日 2025-10
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| 出版者 |
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出版者 |
Wiley |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
2473-4209 |
| DOI |
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識別子タイプ |
DOI |
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関連識別子 |
10.1002/mp.70076 |
