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Promoter/Enhancer Replacement by Genome Editing for Crop Improvement
https://repo.qst.go.jp/records/2001807
https://repo.qst.go.jp/records/20018078f90df56-902d-406f-8e83-76b9227e0fb7
| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2025-12-16 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Promoter/Enhancer Replacement by Genome Editing for Crop Improvement | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| 著者 |
Nobusawa Takashi
× Nobusawa Takashi
× Yamatani Hiroshi
× Kusaba Makoto
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Genome editing is a technology that enables targeted mutagenesis. Notably, SDN-1 genome editing, which does not involve the incorporation of foreign DNA sequences and can introduce the same mutations as naturally occurring mutations, is not subject to GMO regulations in many countries if transgenes are segregated out. This makes it an attractive strategy for crop improvement. Multiple DNA double-strand breaks introduced via genome editing may lead to inversions or translocations. If these genomic alterations involve promoter regions, a promoter/enhancer replacement may occur, thereby altering target gene expression as desired. To date, such gain-of-function traits have only been achieved through GMOs. Thus, promoter/enhancer replacement by genome editing represents a new paradigm in genome editing for crop improvement. | |||||||||||
| 書誌情報 |
Trends in Plant Science p. 1360-1385, 発行日 2025-11 |
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| 出版者 | ||||||||||||
| 出版者 | Cell Press | |||||||||||
| DOI | ||||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | 10.1016/j.tplants.2025. | |||||||||||
