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High-Fat Diet and Altered Radiation Response
https://repo.qst.go.jp/records/2001775
https://repo.qst.go.jp/records/2001775a590e4cb-fe0c-4404-9023-490386c44de1
| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2025-04-01 | |||||||||||
| タイトル | ||||||||||||
| タイトル | High-Fat Diet and Altered Radiation Response | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| 著者 |
Kantapan Jiraporn
× Kantapan Jiraporn
× Katsube Takanori
× Wang Bing
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | High-fat diets (HFDs) are becoming increasingly prevalent and are a major contributor to the rising incidence of obesity and metabolic disorders, including diabetes and heart disease. At the same time, exposure to ionizing radiation (IR) from medical procedures, environmental sources, and occupational settings remains a significant public concern. This review explores the interplay between HFDs and IR, focusing on their combined effects on metabolism, immune function, and DNA repair mechanisms. We found that HFDs can exacerbate radiation-induced damage by increasing oxidative stress, inflammation, and DNA damage, potentially elevating the risk of chronic diseases. Surprisingly, in some cases, HFDs also trigger cellular changes that reduce the efficacy of radiation therapy in cancer treatment. Furthermore, maternal HFD exposure can increase radiation sensitivity in offspring, particularly males, by disrupting immune and metabolic functions. Understanding the influence of diet on radiation response is crucial for developing effective public health strategies. The timing and composition of dietary intake in the context of radiation exposure are key considerations for optimizing public health interventions, improving cancer treatment outcomes, and minimizing radiation-related health risks. We encourage collaborative dietary and lifestyle interventions aimed at reducing chronic disease risk and enhancing health outcomes, particularly among vulnerable populations. This review provides evidence to guide such efforts toward improved health and therapeutic outcomes. | |||||||||||
| 書誌情報 |
Biology 巻 14, 号 4, p. 324-324, 発行日 2025-04 |
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| ISSN | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 2079-7737 | |||||||||||
| DOI | ||||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | 10.3390/biology14040324 | |||||||||||
