| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-04-01 |
| タイトル |
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|
タイトル |
Decomposition of hydrogen peroxide by gold nanoparticles leading to increase of OH radical yields: A radiosensitization potential for hadron therapy |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Kusumoto Tamon
Okazaki Yu
Hirayama Ryoichi
Kataoka Jun
Roux Stephane
Fromm Michel
Bazzi Rana
Kodaira Satoshi
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
We discuss the increase of OH radicals due to the decomposition of hydrogen peroxide in the presence of gold nanoparticles (GNPs) under protons and heavy ion irradiations of aqueous solutions. Hydrogen peroxide formed by water radiolysis is decomposed by GNPs. Due to the decomposition of hydrogen peroxide, yields of OH radicals increase. The conversion efficiency to OH radicals due to hydrogen peroxide decomposition for protons and heavy ions is measured to be lower than the previously obtained one under X-rays. As the observed increase in OH radicals reinforce the contribution of the indirect action of radiation, this leads to an improvement in biological efficacy, so that GNPs would become applicable to hadron therapy. |
| 書誌情報 |
Radiation Physics and Chemistry
巻 232,
p. 112687,
発行日 2025-07
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| 出版者 |
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出版者 |
ELSEVIER |
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1879-0895 |
| DOI |
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識別子タイプ |
DOI |
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関連識別子 |
10.1016/j.radphyschem.2025.112687 |
