| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-03-11 |
| タイトル |
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|
タイトル |
Physical parameters and biological factors affect the abscopal effect of combining radiotherapy with immunotherapy: an update on preclinical works |
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言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Wangcai Ren
Jialing Wen
Gang Guo
Wenchao Gu
Shenke Zhang
Chang Liu
Kensuke Osada
Takashi Shimokawa
Qiaojuan Wang
Yue Wang
Xuanzhang Tu
Chen Li
Li Sui
Liqiu Ma
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
In the process of radiotherapy for cancer patients, there is an extremely low probability phenomenon that the distal tumor/metastasis away from the irradiation field undergoes regression after localized radiation therapy, which is called the abscopal effect. Enhancing the incidence of this phenomenon possesses profound significance for the investigation of metastatic cancer treatment. Currently, the underlying mechanisms of the abscopal effect remain unclear. Radiation-induced immunogenic cell death is considered one of the potential mechanisms for the abscopal effect. From this perspective, we explored how physical parameters and biological factors influence this process. Differences between patients with respect to physical factors and intrinsic biological factors that activate the immune response (acquired factors) may affect the induction of the abscopal effect. |
| 書誌情報 |
Frontiers in Public Health
発行日 2025-01
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| PubMed番号 |
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識別子タイプ |
PMID |
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関連識別子 |
39949344 |
| DOI |
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|
識別子タイプ |
DOI |
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関連識別子 |
10.3389/fpubh.2024.1517147 |
