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アイテム
Comparative Analysis of Photon Stereotactic Radiotherapy and Carbon-Ion Radiotherapy for Elderly Patients with Stage I Non-Small-Cell Lung Cancer: A Multicenter Retrospective Study.
https://repo.qst.go.jp/records/2000868
https://repo.qst.go.jp/records/20008682a1e46cc-48e0-40b8-a084-21d9e973d4f1
| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||||||||
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| 公開日 | 2025-04-17 | |||||||||||||||||||||||||||
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| タイトル | Comparative Analysis of Photon Stereotactic Radiotherapy and Carbon-Ion Radiotherapy for Elderly Patients with Stage I Non-Small-Cell Lung Cancer: A Multicenter Retrospective Study. | |||||||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||||||||
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| 言語 | eng | |||||||||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||||||||
| 著者 |
Shuri Aoki
× Shuri Aoki
× Hiroshi Onishi
× Masataka Karube
× Naoyoshi Yamamoto
× Hideomi Yamashita
× Yoshiyuki Shioyama
× Yasuo Matsumoto
× Yukinori Matsuo
× Akifumi Miyakawa
× Haruo Matsushita
× Hitoshi Ishikawa
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| 抄録 | ||||||||||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||||||||||
| 内容記述 | The emergence of an aging society and technological advances have made radiotherapy, especially stereotactic body radiotherapy (SBRT), a common alternative to surgery for elderly patients with early stage non-small-cell lung cancer (NSCLC). Carbon-ion radiotherapy (CIRT) is also an attractive treatment option with potentially lower toxicity for elderly patients with comorbidities. We compared the clinical outcomes of the two modalities using Japanese multicenter data. SBRT (n = 420) and single-fraction CIRT (n = 70) data for patients with stage I NSCLC from 20 centers were retrospectively analyzed. Contiguous patients ? 80 years of age were enrolled, and overall survival (OS), disease-specific survival (DSS), local control (LC), and adverse event rates were compared. The median age was 83 years in both groups and the median follow-up periods were 28.5 and 42.7 months for SBRT and CIRT, respectively. The 3-year OS, DSS, and LC rates were 76.0% vs. 72.3% ( = 0.21), 87.5% vs. 81.6% ( = 0.46), and 79.2% vs. 78.2% ( = 0.87), respectively, for the SBRT vs. CIRT groups. Regarding toxicity, 2.9% of the SBRT group developed grade ? 3 radiation pneumonitis, whereas none of the CIRT group developed grade ? 2 radiation pneumonitis. SBRT and CIRT in elderly patients showed similar survival and LC rates, although CIRT was associated with less severe radiation pneumonitis. | |||||||||||||||||||||||||||
| 書誌情報 |
Cancers 巻 15, 号 14, p. 3633, 発行日 2023-07 |
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| 出版者 | MDPI | |||||||||||||||||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||||||
| 収録物識別子 | 2072-6694 | |||||||||||||||||||||||||||
| PubMed番号 | ||||||||||||||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||||||||||||||
| 関連識別子 | 37509294 | |||||||||||||||||||||||||||
| DOI | ||||||||||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||||||||
| 関連識別子 | 10.3390/cancers15143633 | |||||||||||||||||||||||||||
