| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-03-13 |
| タイトル |
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タイトル |
Hyperpolarization of Biomolecules in Eutectic Crystals at Room Temperature Using Photoexcited Electrons |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Sato Haruki
Miyanishi Koichiro
Negoro Makoto
Kagawa Akinori
Nishiyama Yusuke
Horike Satoshi
Nakamura Koichi
Inukai Munehiro
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
The hyperpolarization of biomolecules at room temperature could facilitate highly sensitive magnetic resonance imaging for metabolic studies and nuclear magnetic resonance (NMR)-based screenings for drug discovery. In this study, we demonstrate the hyperpolarization of biomolecules in eutectic crystals using photoexcited triplet electrons at room temperature. Eutectic crystals composed of the domains of benzoic acid doped with the polarization source and analyte domains were prepared using a melting?quenching process. Spin diffusion between the benzoic acid and analyte domain was elucidated using solid-state NMR analysis, indicating that hyperpolarization was transferred from the domain of benzoic acid to the domain of the analyte. |
| 書誌情報 |
The Journal of Physical Chemistry Letters
巻 14,
号 19,
p. 4560-4564,
発行日 2023-05
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| 出版者 |
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出版者 |
ACS Publications |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1948-7185 |
| PubMed番号 |
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識別子タイプ |
PMID |
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関連識別子 |
37159560 |
| DOI |
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識別子タイプ |
DOI |
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関連識別子 |
10.1021/acs.jpclett.3c00622 |
