| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2024-07-04 |
| タイトル |
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タイトル |
SARS-CoV-2 Omicron detection by antigen tests using saliva |
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言語 |
ja |
| 言語 |
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言語 |
jpn |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Kaoru Murakami
Sumio Iwasaki
Satoshi Oguri
Kumiko Tanaka
Rigel Suzuki
Kasumi Hayasaka
Shinichi Fujisawa
Chiaki Watanabe
Satoshi Konno
Isao Yokota
Takasuke Fukuhara
Masaaki Murakami
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
The Omicron emerged in November 2021 and became the predominant SARS-CoV-2 variant globally. It spreads more rapidly than ancestral lineages and its rapid detection is critical for the prevention of disease outbreaks. Antigen tests such as immunochromatographic assay (ICA) and chemiluminescent enzyme immunoassay (CLEIA) yield results more quickly than standard polymerase chain reaction (PCR). However, their utility for the detection of the Omicron variant remains unclear. We herein evaluated the performance of ICA and CLEIA in saliva from 51 patients with Omicron and 60 PCR negative individuals. The sensitivity and specificity of CLEIA were 98.0% (95%CI: 89.6-100.0%) and 100.0% (95%CI: 94.0-100.0%), respectively, with fine correlation with cycle threshold (Ct) values. The sensitivity and specificity of ICA were 58.8% (95%CI: 44.2-72.4%) and 100.0% (95%CI: 94.0-100.0%), respectively. The sensitivity of ICA was 100.0% (95%CI: 80.5-100.0%) when PCR Ct was less than 25. The Omicron can be efficiently detected in saliva by CLEIA. ICA also detects high viral load Omicron using saliva. |
| 書誌情報 |
Journal of Clinical Virology Plus
巻 2,
号 4,
p. 100109,
発行日 2022-11
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| 出版者 |
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出版者 |
Elsevier |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
2667-0380 |
| DOI |
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識別子タイプ |
DOI |
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関連識別子 |
10.1016/j.jcvp.2022.100109 |
