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A Custom Mouthpiece With Lip Bumper for Osteoradionecrosis Risk Reduction After Carbon-Ion Radiation Therapy for Adenoid Cystic Carcinoma of the Lip.
https://repo.qst.go.jp/records/2000490
https://repo.qst.go.jp/records/2000490d033d86e-e49c-4800-9113-565f2c58194b
| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||
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| 公開日 | 2024-05-23 | |||||||||||||||||||||
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| タイトル | A Custom Mouthpiece With Lip Bumper for Osteoradionecrosis Risk Reduction After Carbon-Ion Radiation Therapy for Adenoid Cystic Carcinoma of the Lip. | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
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| 言語 | eng | |||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||
| 著者 |
Hiroaki Ikawa
× Hiroaki Ikawa
× Masashi Koto
× Daniel K Ebner
× Hirotoshi Takiyama
× Makoto Shinoto
× Akihiro Nomoto
× Shigeru Yamada
× Hiroshi Tsuji
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| 抄録 | ||||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||||
| 内容記述 | The lips are a common location for minor salivary gland tumors, including adenoid cystic carcinoma (ACC).1 Surgery is the preferred treatment for ACC, although patients who refuse or are ineligible for surgery may receive radiation therapy (RT).2 However, conventional RT is ineffective in treating ACC due to inherent radioresistance. Carbon-ion radiation therapy (CIRT) has demonstrated efficacy with acceptable toxicity.3 Consequently, CIRT has been viewed as adaptable to treat ACC of the lip. Osteoradionecrosis (ORN) is a serious adverse event in patients with head and neck cancer who receive CIRT. Grade ?2 maxillary ORN after CIRT was reported at 19.0% in 2014.4 Further study demonstrated that the maxillary volume receiving >50 Gy (relative biological effectiveness [RBE], V50) CIRT delivered in 16 fractions, along with the inclusion of teeth within the planning target volume (PTV), are significant independent risk factors for ORN.4 To reduce the risk of maxillary ORN, a reduction of V50 is required, and intraoral devices are one modality by which the lip and jaw are positioned to reduce the dose. However, no devices to prevent ORN from lip cancer have been reported for CIRT. In this technical report, we introduce and evaluate the efficacy of a custom-made mouthpiece with a lip bumper for the reduction of maxilla V50 in patients with ACC of the lip(s) treated with CIRT. |
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| 書誌情報 |
Advances in radiation oncology 巻 8, 号 1, p. 101114, 発行日 2024-01 |
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| 出版者 | Elsevier | |||||||||||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||
| 収録物識別子 | 2452-1094 | |||||||||||||||||||||
| PubMed番号 | ||||||||||||||||||||||
| 識別子タイプ | PMID | |||||||||||||||||||||
| 関連識別子 | 36471821 | |||||||||||||||||||||
| DOI | ||||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||
| 関連識別子 | 10.1016/j.adro.2022.101114 | |||||||||||||||||||||
