| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2024-02-16 |
| タイトル |
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|
タイトル |
Biokinetic model analysis with DTPA administration for a case of accidental inhalation of actinides in Japan |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Tani Kotaro
Ishigure Nobuhito
Kim Eunjoo
Tominaga Takako
Tatsuzaki Hideo
Akashi Makoto
Kurihara Osamu
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| 抄録 |
|
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内容記述タイプ |
Abstract |
|
内容記述 |
Accidental inhalation intake of plutonium isotopes and 241Am occurred at a Pu research facility in Japan in 2017, and five workers involved in this accident were treated by the administration of Ca/Zn-diethylenetriaminepentaaceticacid (DTPA). For the worker who was most internally exposed, the therapy was continued over one year after the accident. Urinary samples collected before and after each administration were subject to bioassay to evaluate the efficacy of the dose reduction. This study performed numerical analyses using a biokinetic model dealing with 241Am-DTPA with reference to the European Coordinated Network on Radiation Dosimetry (CONRAD) approach, which assumes that the complex of actinides and Ca/Zn-DTPA is generated in the designated compartments in the biokinetic model. The results of the model prediction well captured the trend of the observed urinary excretion in the long-term bioassay and would be useful to evaluate the efficacy of the Ca/Zn-DTPA administration for the worker involved in the accident. |
| 書誌情報 |
Radiation Protection Dosimetry
巻 199,
号 15-16,
p. 2025-2029,
発行日 2023-10
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| 出版者 |
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出版者 |
Oxford University Press |
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1742-3406 |
| DOI |
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|
識別子タイプ |
DOI |
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関連識別子 |
10.1093/rpd/ncac224 |
