| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2023-11-30 |
| タイトル |
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|
タイトル |
Time-of-flight based neutron background reduction in secondary-electron-bremsstrahlung imaging for in-vivo range verification of proton therapy: a Monte Carlo study |
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言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Yabe Takuya
Yamaguchi Mitsutaka
Tsuda Michiko
Nagao Yuuto
Kawachi Naoki
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
In proton therapy, range verification is important to monitor the location of the Bragg peak within the patient's body. Secondary-electron-bremsstrahlung (SEB) imaging is a promising method of proton range verification. Unfortunately, the SEB images measured by the dedicated gamma camera contain neutron-induced backgrounds as well as the SEB counts. To improve the accuracy of range verification in SEB imaging, we proposed to apply a time-of-flight (TOF) method to reduce neutron background in measured images of SEB. The SEB and neutron generation and transport were calculated by a Monte Carlo simulation. Proton pencil beams were irradiated to a water phantom and then the time spectra and profiles of SEB and neutron were obtained by scoring on a detector. The total count of neutrons was approximately 10 times higher than that of SEB and increased with higher proton energy. The TOF method, selecting a time window for the TOF spectrum of SEB, reduced the neutron background by more than 97%. We concluded that the TOF methods can dramatically reduce neutron background and improve the accuracy of proton range verification in SEB imaging. |
| 書誌情報 |
Journal of Instrumentation (JINST)
巻 18,
p. C02041,
発行日 2023-02
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| 出版者 |
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出版者 |
IOP Publishing |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1748-0221 |
| DOI |
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識別子タイプ |
DOI |
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関連識別子 |
10.1088/1748-0221/18/02/C02041 |
