量研学術機関リポジトリ「QST-Repository」は、国立研究開発法人 量子科学技術研究開発機構に所属する職員等が生み出した学術成果（学会誌発表論文、学会発表、研究開発報告書、特許等）を集積しインターネット上で広く公開するサービスです。 Welcome to QST-Repository where we accumulates and discloses the academic research results(Journal Publications, Conference presentation, Research and Development Report, Patent, etc.) of the members of National Institutes for Quantum Science and Technology.
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We objectively compared C-11 methionine (MET) PET/CT and contrast-enhanced (CE) CT images to clarify the difference in diagnostic information using fusion software with a registration algorithm. Eleven patients with adenoid cystic carcinoma (ACC) and twelve patients with malignant melanoma (MM) in head and neck region were studied PET/CT as well as CECT obtained separately. All patients received PET/CT and CECT before carbon ion radiotherapy (CIRT) and fifteen patients received both studies after CIRT. CT image from PET/CT and CECT image were registered automatically by PMOD software based on Mutual Information. And then CT image from PET/CT was replaced with PET image from PET/CT and we got PET/CECT fusion image, and were evaluated according to the four-grade system such as "Matched" with each other, "Embraced " the other, partially "Overlapped" and "Separated" with
each other. Matched-grade,Embraced-grade,verlapped -grade and Separated-grade were
42.1%,39.5%,7.9% and 10.5% in all studies, respectively. Combination of Matched and Embraced-grade was 72.7% studies in ACC and 93.8% studies in MM. Before CIRT, it was 100% in ACC and 91.7% in MM. After CIRT, it was 45.5% in ACC and 100% in MM. MET accumulation and CT enhancement area tended to match before CIRT, but tended to mismatch after CIRT in ACC. It also tended to match mostly both before and after CIRT in MM.
頭頸部腫瘍におけるPETによるメチオニン集積範囲とCT造影範囲の対比検討
