量研学術機関リポジトリ「QST-Repository」は、国立研究開発法人 量子科学技術研究開発機構に所属する職員等が生み出した学術成果（学会誌発表論文、学会発表、研究開発報告書、特許等）を集積しインターネット上で広く公開するサービスです。 Welcome to QST-Repository where we accumulates and discloses the academic research results(Journal Publications, Conference presentation, Research and Development Report, Patent, etc.) of the members of National Institutes for Quantum and Radiological Science and Technology.
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The National Institute of Radiological Sciences (NIRS) is the national center for radiation emergency medical preparedness in the nuclear disaster prevention system of Japan. Since the Fukushima Nuclear Power Station accident on March 11, 2011, NIRS has received many requests by e-mail and phone from colleagues throughout the world including those of WHO BioDoseNet.
Currently three staff members of the Research Center for Radiation Emergency Medicine have been on standby for biodosimetry of workers at the accident site with storage of as many as 1,000 Dicentric Analysis tests and two sets of AXIO Imager.Z2 (Carl Zeiss, Inc.) equipped with a CCD camera and Metafer 4 (MetaSystems GmbH), one of which has been lent gratuitously by courtesy of these companies.
In principle, following the IAEA Technical Reports Series No. 405 "Cytogenetic Analysis for Radiation Dose Assessment", Vienna, 2001 (http://www-pub.iaea.org/MTCD/publications/PDF/TRS405_scr.pdf), we perform cell culture, and accomplish a triage-scoring on the day of cell fixation and dose estimation with our calibration curve using a Cs-137 source within a day or two. When necessary, members of the Japan Chromosome Network consisting of nine laboratories will be asked for assistance.
For three months, we received nine blood samples from workers for Dicentric Analysis. Fortunately their doses of external exposure were relatively low, and thus we scored 100 cells / donor for triage and 1,000 cells / donor for dose estimation.
In this instance we have simultaneously faced a nuclear disaster and large earthquakes covering a wide area of our country; the transportation system was paralyzed and the supply of electricity was stopped for a while. Moreover, laboratories and suppliers (machines, reagents, and buildings) were damaged in Tohoku district; some staff members of our center became refugees in the first few days after the earthquakes.
As a lesson learned, in future a much better backup system should be established in Japan to prepare for the worst scenario. Lastly we are very thankful for the offers of help extended to us so far.
雑誌名
REMPAN e-Newsletter (Online Only : URL:http://rempan.uk-wuerzburg.de/en/downloads.html)
REMPAN Response to Fukushima - Biodosimetry for workers at Fukushima Nuclear Power Station
