量研学術機関リポジトリ「QST-Repository」は、国立研究開発法人 量子科学技術研究開発機構に所属する職員等が生み出した学術成果(学会誌発表論文、学会発表、研究開発報告書、特許等)を集積しインターネット上で広く公開するサービスです。 Welcome to QST-Repository where we accumulates and discloses the academic research results(Journal Publications, Conference presentation, Research and Development Report, Patent, etc.) of the members of National Institutes for Quantum Science and Technology.
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Abstract: Electroporation-based cancer treatment techniques are currently after active investigations in the field of drug delivery, optimization of electrical parameters and elucidation of the exact mechanisms at a molecular level. The present study is designed to investigate the exact in vivo redistribution and persistence of nanoparticles in the tumor tissue
f colon-cancer grafted mice after electroporation with two different kinds of electrodes.The aim of the study is to avoid artifacts during electroporation due to accumulation of nanoparticles in the surrounding non-cancer tissues. The isolated electrodes are appropriate for the treatment of 3-dimensional tumors and have a large potential in this field. Keywords: Electroassisted drug delivery, in vivo imaging, Cancer, Nanoparticles, Quantum dots.