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Efficacy of Spacers in Radiation Therapy for Locally Advanced Pancreatic Cancer: A Planning Study
https://repo.qst.go.jp/records/82366
https://repo.qst.go.jp/records/8236655064e0b-fb34-4e4d-9610-07214305524b
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2021-03-22 | |||||
タイトル | ||||||
タイトル | Efficacy of Spacers in Radiation Therapy for Locally Advanced Pancreatic Cancer: A Planning Study | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Hiroki Kawaguchi
× Hiroki Kawaguchi× Demizu, Yusuke× Naritoshi, Mukumoto× Ishihara, Takeaki× Daisuke, Miyawaki× Komatsu , Shohei× Hiroaki, Akasaka× Makoto, Shinoto× Yoshiyuki, Shioyama× Katsumasa, Nakamura× Fukumoto, Takumi× Ryohei, Sasaki× Naritoshi, Mukumoto× Daisuke, Miyawaki× Hiroaki, Akasaka× Makoto, Shinoto× Yoshiyuki, Shioyama× Katsumasa, Nakamura× Ryohei, Sasaki |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background/aim: We aimed to investigate the dosimetric effects of a spacer placed between the pancreas and surrounding gastrointestinal structures in intensity-modulated radiation therapy (IMRT) planning to provide more effective radiation therapy for locally advanced pancreatic cancer (LAPC). Patients and methods: Treatment planning was performed for six patients with LAPC based on computed tomography images without spacers and with 5-mm or 10-mm spacers virtually inserted under the supervision of a hepatobiliary pancreatic surgeon. The prescription dose was 63 Gy in 28 fractions. Results: With the exception of one case of pancreatic head cancer, planning target volume receiving ≥95% of the prescribed dose (PTV V95) was achieved by 90% or more by inserting a spacer, and by 95% or more in all 3 cases of pancreatic body and tail cancer by inserting a 10-mm spacer. Conclusion: IMRT with appropriate spacer placement may help provide high-dose treatment for LAPC and improve associated patient outcomes. |
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書誌情報 |
Anticancer research 巻 41, 号 1, p. 503-508, 発行日 2021-01 |
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出版者 | ||||||
出版者 | International Institute of Anticancer Research | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0250-7005 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 33419849 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.21873/anticanres.14801 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://ar.iiarjournals.org/content/41/1/503#:~:text=Results%3A%20With%20the%20exception%20of,inserting%20a%2010%2Dmm%20spacer. |