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エピジェネティクスの分子機構の動的理解と今後の発展 －電子スピン共鳴と有機合成とタンパク質研究と，その将来について－
https://repo.qst.go.jp/records/84975
https://repo.qst.go.jp/records/849753ce82886-569c-4228-8186-afbdcf902ea6
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2022-02-18 | |||||
| タイトル | ||||||
| タイトル | エピジェネティクスの分子機構の動的理解と今後の発展 －電子スピン共鳴と有機合成とタンパク質研究と，その将来について－ | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
末武, 勲
× 末武, 勲× 松尾, 龍人× 武藤, 梨沙× 宗, 正智× 三島, 優一× 北條, 裕信× Tatsuhito, Matsuo |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Epigenetics is an emerging field of science that studies heritable changes caused by activation and deactivation of genes without any change in the genomic DNA information. In other words, epigenetics is the study to elucidate how environment and our behavior can cause changes that affect the way our genes function. Many types of regulatory mechanisms in epigenetics, such as DNA modification and numerous types of histone modification has been reported. Steady state recognition of histone modifications and their localizations on genome has been reported, however, it is still uncertain how the modification is dynamically recognized and contribute for establishing higher order structure in nuclei. In this article, we introduce our recent trials to analyze protein with chemical modifications and/or intrinsic disorder regions by combining biochemistry, organic chemistry and ESR, and also show future plan to utilize neutron scattering to further characterize the relevant proteins. | |||||
| 書誌情報 |
日本中性子科学会誌「波紋」 巻 32, 号 １, p. 33-37, 発行日 2022-02 |
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| 出版者 | ||||||
| 出版者 | 日本中性子科学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1349-046X | |||||
