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Radiosynthesis of 18F-fluoroethylated tracers via a simplified one-pot 18F-fluoroethylation method using [18F]fluoroethyl tosylate
https://repo.qst.go.jp/records/81614
https://repo.qst.go.jp/records/8161409d91cc2-9af2-40f5-b0d9-7d6e9547fb94
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-12-21 | |||||
タイトル | ||||||
タイトル | Radiosynthesis of 18F-fluoroethylated tracers via a simplified one-pot 18F-fluoroethylation method using [18F]fluoroethyl tosylate | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Kawamura, Kazunori
× Kawamura, Kazunori× Kumata, Katsushi× Mori, Wakana× Fujinaga, Masayuki× Kurihara, Yusuke× Ogawa, Masanao× Ohkubo, Takayuki× Furutsuka, Kenji× Hashimoto, Hiroki× Nengaki, Nobuki× Ming-Rong, Zhang× Kazunori, Kawamura× Katsushi, Kumata× Wakana, Mori× Masayuki, Fujinaga× Kurihara, Yusuke× Masanao, Ogawa× Ohkubo, Takayuki× Kenji, Furutsuka× Hiroki, Hashimoto× Nobuki, Nengaki× Zhang, Ming-Rong |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Recently, a straightforward one-pot method for 18F-fluoroethylation without azeotropic drying of cyclotron-produced [18F]F– was developed. In this study, we have attempted to simplify the automated radiosynthesis of two [18F]fluoroethylated tracers, [18F]FEDAC and [18F]FET, using a desmethyl labeling precursor and [18F]fluoroethyl tosylate, based on the above-mentioned method. The radiochemical yields of [18F]FEDAC and [18F]FET were 26 ± 3.7% (n = 5) and 14 ± 2.2% (n = 4), respectively, based on total [18F]F– at the end of irradiation. | |||||
書誌情報 |
Applied Radiation and Isotopes 巻 169, p. 109571, 発行日 2021-03 |
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出版者 | ||||||
出版者 | ELSEVIER | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0969-8043 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.apradiso.2020.109571 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.sciencedirect.com/science/article/pii/S0969804320307090 |