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A single-ended readout four-layer DOI detector with 1 mm crystal pitch for high resolution small animal imaging

https://repo.qst.go.jp/records/76863
https://repo.qst.go.jp/records/76863
3d29653f-a5f8-4ea3-8d64-740ca80d22bf
Item type 会議発表用資料 / Presentation(1)
公開日 2019-09-19
タイトル
タイトル A single-ended readout four-layer DOI detector with 1 mm crystal pitch for high resolution small animal imaging
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Kang, Hangyu

× Kang, Hangyu

WEKO 785034

Kang, Hangyu

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Obata, Fujino

× Obata, Fujino

WEKO 785035

Obata, Fujino

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Nishikido, Fumihiko

× Nishikido, Fumihiko

WEKO 785036

Nishikido, Fumihiko

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Yamaya, Taiga

× Yamaya, Taiga

WEKO 785037

Yamaya, Taiga

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Kang, Hangyu

× Kang, Hangyu

WEKO 785038

en Kang, Hangyu

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Obata, Fujino

× Obata, Fujino

WEKO 785039

en Obata, Fujino

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Nishikido, Fumihiko

× Nishikido, Fumihiko

WEKO 785040

en Nishikido, Fumihiko

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Yamaya, Taiga

× Yamaya, Taiga

WEKO 785041

en Yamaya, Taiga

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抄録
内容記述タイプ Abstract
内容記述 Depth of interaction (DOI) encoding positron emission tomography (PET) can visualize the 3D distribution of radiopharmaceuticals in animal with high resolution. The aim of this study is to develop a single-ended readout four-layer DOI PET detector with a 1 mm crystal pitch for high resolution small animal imaging. The proposed four-layer DOI crystal block consists of an 8 × 8 LYSO crystal array (1 × 1 × 5 mm3) stacked in four-layer which yielded a total thickness of 20 mm (Fig.1). The DOI information was encoded into a 2D flood histogram, by using a combination of enhanced specular reflector (ESR) and room temperature vulcanizing (RTV) rubber (Fig. 2(a))[1]. The scintillation light were readout by using a 4 × 4 SiPM array (Hamamatsu, S13361-3050NE-04, Japan) with a pixel pitch of 3.2 mm. The sixteen SiPM output signals were multiplexed into four positional signals (A, B, C, and D) and then digitized by using CAMAC DAQ. A Na-22 point source was used to irradiate 511 keV gamma photon to the LYSO crystal array. Most of the LYSO crystals could be identified in 2D flood histogram except at the corner region (Fig. 2(b)). The energy resolutions of the 1st, 2nd, 3rd, and 4th layers were 11%, 15%, 13%, and 32%, respectively (Fig.2(c)). In conclusion, a single-ended readout four-layer DOI PET detector was developed. In future, a prototype small animal PET scanner will be developed for high resolution and high-sensitivity molecular imaging.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 15th Int. SCINT 2019
発表年月日
日付 2019-10-01
日付タイプ Issued
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