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Feasibility study of real-time tumor tracking by OpenPET during radiotherapy
https://repo.qst.go.jp/records/71047
https://repo.qst.go.jp/records/71047ccf42883-e6f0-48bf-abc7-b595a354c790
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-02-14 | |||||
| タイトル | ||||||
| タイトル | Feasibility study of real-time tumor tracking by OpenPET during radiotherapy | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Tashima, Hideaki
× Tashima, Hideaki× Yoshida, Eiji× Shinaji, Tetsuya× Hirano, Yoshiyuki× Kinouchi, Shoko× Nishikido, Fumihiko× Suga, Mikio× Haneishi, Hideaki× Ito, Hiroshi× Yamaya, Taiga× 田島 英朗× 吉田 英治× 品地 哲弥× 平野 祥之× 木内 尚子× 錦戸 文彦× 菅 幹生× 羽石 秀昭× 伊藤 浩× 山谷 泰賀 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | 1) Introduction We are developing the OpenPET, which can provide an open space observable and accessible to the patient during PET measurements. One of the applications for the OpenPET is real-time tumor tracking which can realize real-time PET-guided radiation therapy. We have developed real-time imaging system for the OpenPET and implemented it on the small OpenPET prototype. The developed system demonstrated ability to track a moving point source positioned in the open space. In actual situations, however, radioactivity concentrates not only tumor but also surrounding organs and it is uncertain whether the tumor tracking is feasible in human body. In this study, we conducted a Monte Carlo simulation to investigate the conditions under which the tumor tracking by human-sized OpenPET is feasible. 2) Method For a realistic simulation, we used the 4D extended cardiac-torso (XCAT) phantom, which is a realistic 4D human whole body phantom, and assigned 18F-FDG standardized uptake values (SUVs) to normal organs based on the literature. As a Monte Carlo simulation toolkit, we used geant4 application for tomographic emission (GATE) ver. 6.1. A sphere-shaped tumor was placed on upper left lung. List-mode data were generated for each 0.5 s time frame of a respiratory cycle of 5 s with various tumor sizes and SUVs. 4D images were reconstructed in a frame-by-frame manner and tumor position was automatically extracted for each time frame by a pattern matching technique. 3) Result The mean error of the tumor positions extracted from the reconstructed images with time frames of 0.5 s was similar to the PET image resolution when the tumor had radioactivity concentration above certain amount. 4) Conclusion We showed that tumor tracking by the OpenPET is feasible even in the human body scale and for realistic conditions. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 第3回分子追跡放射線治療国際会議 | |||||
| 発表年月日 | ||||||
| 日付 | 2013-02-08 | |||||
| 日付タイプ | Issued | |||||
