WEKO3
アイテム
Carbon-Ion Therapy for Patients with Locally Recurrent Rectal Cancer
https://repo.qst.go.jp/records/64000
https://repo.qst.go.jp/records/64000cce5e8ec-9918-441d-ad07-d7799f295cc3
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-09-15 | |||||
| タイトル | ||||||
| タイトル | Carbon-Ion Therapy for Patients with Locally Recurrent Rectal Cancer | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Yamada, Shigeru
× Yamada, Shigeru× Shinoto, Makoto× Oonishi, Kazuhiko× Yasuda, Shigeo× Imada, Hiroshi× Kamada, Tadashi× Tsujii, Hirohiko× 山田 滋× 篠藤 誠× 大西 和彦× 安田 茂雄× 今田 浩史× 鎌田 正× 辻井 博彦 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: To evaluate the tolerance for and effectiveness of carbon ion radiotherapy in patients with locally recurrent rectal cancer. Patients and Methods: We conducted a phase I/II dose escalation study of carbon ion radiotherapy. One hundred twenty-nine patients with 134 sites of locally recurrent cancer receiving carbon ion radiotherapy were analyzed. Fifty-eight relapses originated in the presacral region, 45 in the pelvic sidewalls, 20 in the perineal region and 9 in the colorectal anastomosis. The total dose ranged from 67.2 to 73.6 gray equivalent (GyE) and was administered in 16 fixed fractions over 4 weeks (4.2 to 4.6 GyE/fraction). Results: None of the 104 lesions treated with the highest total dose of 73.6 GyE experienced National Cancer Institute - Common Toxicity Criteria grade 3 to 5 acute reactions. The local control rate in patients treated with 73.6 GyE in the present study was 98% at one year and 95% at 5 years. The dose escalation was then halted at this level. The median survival in the patients treated with 73.6 GyE was 54 months (range, 7 to 82 months), and the overall survival rates were 74% at 3 years and 45% at 5 years, respectively. Conclusion: Carbon ion radiotherapy seems to be a safe and effective modality in the management of locally recurrent rectal cancer, providing good local control and offering a survival advantage without unacceptable |
|||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The 4th Japanese-European Joint Symposium on Ion Cancer Therapy | |||||
| 発表年月日 | ||||||
| 日付 | 2010-09-11 | |||||
| 日付タイプ | Issued | |||||
