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Dose and Particle Dependence of Fluorescent Dots in DNA Sheet Observed with Fluorescence Imaging of Oxidative Damage of Guanine Induced by Heavy Ion irradiation at TIARA
https://repo.qst.go.jp/records/56044
https://repo.qst.go.jp/records/560448b3ac5dc-3afc-46a2-9af0-e6f0c78337f2
Item type | 一般雑誌記事 / Article(1) | |||||
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公開日 | 2017-04-28 | |||||
タイトル | ||||||
タイトル | Dose and Particle Dependence of Fluorescent Dots in DNA Sheet Observed with Fluorescence Imaging of Oxidative Damage of Guanine Induced by Heavy Ion irradiation at TIARA | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
伊藤, 敦 (東海大)
× 伊藤, 敦 (東海大)× 大内, 章央 (東海大)× 後田, 藤太 (東海大)× 平山, 亮一× 古澤, 佳也× 舟山, 知夫× 横田, 裕一郎× 平山 亮一× 古澤 佳也× 舟山 知夫× 横田 裕一郎 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | To confirm a contribution of the low LET region of heavy-ion track, we irradiated DNA sheet with argon or proton beam, visualize the penumbra region with the aid of an immunofluorescence method using an antibody against 8-OHdG, and examined numbers and areas of the fluorescence dots in the DNA sheet. The result indicated that OH radical induced DNA damage was significantly produced even at very high LET argon ion, but the diameter of fluorescent dot was different from Chatterjee and Schaefer estimated from their ion track model. | |||||
書誌情報 |
QST Takasaki Annual Report 2015 p. 121-121, 発行日 2017-03 |
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出版者 | ||||||
出版者 | Takasaki Advanced Radiation Research Institute, QST |