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Cell cycle-correlative bystander effects are co-mediated by DNA-PKcs and ATM kinase after high LET carbon ions irradiation.
https://repo.qst.go.jp/records/55975
https://repo.qst.go.jp/records/559755cf1df0e-6dc1-40fd-8fe9-666a85dc6845
Item type | 一般雑誌記事 / Article(1) | |||||
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公開日 | 2016-03-20 | |||||
タイトル | ||||||
タイトル | Cell cycle-correlative bystander effects are co-mediated by DNA-PKcs and ATM kinase after high LET carbon ions irradiation. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Tu, Wenzhi
× Tu, Wenzhi× Dong, Chen× Konishi, Teruaki× Kobayashi, Alisa× Furusawa, Yoshiya× Uchihori, Yukio× Shao, Chunlin× 小西 輝昭× 小林 亜利紗× 古澤 佳也× 内堀 幸夫 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Radiation-induced bystander effects (RIBE) was demonstrated with accumulated evidence. Recently, several studies have focused on the role of DNA damage and repair in the bystander response, but the heavy ions induced, especially cell cycle-correlative RIBE are still largely unclear. Our present study found that G2/M phase cells had the largest contribution to the RIBE induced by carbon ions irradiation and identified a pivotal role for DNA-PKcs and ATM in this process as two independent factors. |
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書誌情報 |
平成26 年度放射線医学総合研究所 重粒子線がん治療装置等 共同利用研究報告書 巻 HIMAC-143, p. 103-104, 発行日 2015-12 |
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出版者 | ||||||
出版者 | 放射線医学総合研究所 |