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Braggピーク近傍の重粒子イオンを用いたイオン特異的なDNA損傷の誘発と修復
https://repo.qst.go.jp/records/55545
https://repo.qst.go.jp/records/55545f6547594-96d5-4783-965a-e193821796c2
Item type | 一般雑誌記事 / Article(1) | |||||
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公開日 | 2007-05-13 | |||||
タイトル | ||||||
タイトル | Braggピーク近傍の重粒子イオンを用いたイオン特異的なDNA損傷の誘発と修復 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
小西, 輝昭
× 小西, 輝昭× 大熊, 俊介× 安田, 仲宏× 古澤, 佳也× 今関, 等× 檜枝, 光太郎× 小西 輝昭× 大熊 俊介× 安田 仲宏× 古澤 佳也× 今関 等× 檜枝 光太郎 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | CHO-K1 cells were irradiated with proton (LET=11 keV/µm), C ion (LET=730 keV/µm), Si ion (LET =1620 keV/µm), Ar ion (LET=2650 keV/µm) near the Bragg peak to determine ion specific biological effect. The survival curve for proton was obtained and the inactivation cross-section was 0.863 µm2, which indicates that 150 protons are necessary for cell inactivation. DSB induction rates, R were measured using pulse field gel electrophoresis and FAR analysis. The R values for H, C, Si, and Ar ion were 0.0065, 0.137, 0.563, and 0.355DSB/Mbp/Fluence (particles/µm2) respectively. | |||||
書誌情報 |
放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書 巻 2006, p. 100-102, 発行日 2007-04 |
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出版者 | ||||||
出版者 | 放医研 |