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Feasibility of carbon-ion radiotherapy for oral non-squamous cell carcinomas
https://repo.qst.go.jp/records/49403
https://repo.qst.go.jp/records/494033afe777e-4b8e-4239-9079-9ce6829c7e94
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-01-07 | |||||
タイトル | ||||||
タイトル | Feasibility of carbon-ion radiotherapy for oral non-squamous cell carcinomas | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Ikawa, Hiroaki
× Ikawa, Hiroaki× Koto, Masashi× Hayashi, Kazuhiko× Tonogi, Morio× Takagi, Ryo× Nomura, Takeshi× Tsuji, Hiroshi× Kamada, Tadashi× Ikawa, Hiroaki× Koto, Masashi× Hayashi, Kazuhiko× Tonogi, Morio× Takagi, Ryo× Tsuji, Hiroshi× Kamada, Tadashi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Abstract Background: This study evaluated carbon-ion radiotherapy (C-ion RT) for oral non-squamous cell carcinomas (non-SCC). Methods: We retrospectively obtained data from 74 patients who underwent C-ion RT for oral malignancies between April 1997 and March 2016. The C-ion RT was administered in 16 fractions at a total dose of 57.6 or 64.0 Gy (relative biological effectiveness). Results: Forty-three patients had salivary gland carcinomas, 29 patients had mucosal melanoma, and 2 patients had other types of pathologies. The tumors were classified as T1-T3 (24 cases), T4a (21 cases), or T4b (29 cases). The median follow-up was 49 months. The 5-year rates were 78.8% for local control, 36.2% for progression-free survival, and 58.3% for overall survival. Although 10 patients developed grade 3 osteoradionecrosis after C-ion RT, all patients maintained their mastication and deglutition functions after sequestrectomy and prosthesis placement. Conclusion: C-ion RT was effective for oral non-SCC and had acceptable toxicities. |
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書誌情報 |
Head & Neck 巻 41, 号 6, p. 1795-1803, 発行日 2019-06 |
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出版者 | ||||||
出版者 | Wiley | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1043-3074 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1002/hed.25618 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://onlinelibrary.wiley.com/doi/abs/10.1002/hed.25618 |