WEKO3
アイテム
{"_buckets": {"deposit": "57b340a2-faf3-4f28-9eda-3c509002a5c1"}, "_deposit": {"created_by": 1, "id": "48793", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "48793"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00048793", "sets": ["1"]}, "author_link": ["491373", "491376", "491372", "491379", "491375", "491380", "491378", "491371", "491377", "491374"], "item_8_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2018-02", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "16", "bibliographicPageEnd": "12940", "bibliographicPageStart": "12932", "bibliographicVolumeNumber": "9", "bibliographic_titles": [{"bibliographic_title": "Oncotarget"}]}]}, "item_8_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Purpose: To evaluate the efficacy and safety of carbon-ion radiotherapy (CIRT) for patients with lacrimal gland carcionmas (LGCs) with extraorbital extension \nResults: The median follow-up period was 53.7 months. The 5-year local control and overall survival rates were 62% and 65%, respectively. Regarding late toxicities, 12 patients (36.4%) developed Grade 4 optic nerve disorders, including visual losses of the disweased side (N = 8;66.7%), and 1 patient (3.0%) developed a Grade 3 optic nerve disorder. Three patients (9.0%) developed Grade 3 cataracts, 3 (9.0%) developed glaucoma, and 1 (3.0%) developed retinopathy. Two patients (6.1%) had Grade 4 central nervous system necrosis. No Grade 5 late toxicities were observed. The 5-year preservation rate of the ipsilateral eyeball was 86%.\nConclusion: Definitive CIRT is effective for LGCs with extraorbital extension with acceptable toxicity.\nMethods: Thirty-three patients treated with CIRT at our institution were analyzed. Sixteen patients (48.5%) had adenoid cystic carcinoma, 8 (24.2%) had adnocarcinoma not otherwise specified, and 9 (27.3%) had other types of the disease. Thirty patients (90.9%) had T4c tumors. the prescribed doses were 57.6 Gy (relative biological effectiveness [RBE]) (N = 18; 54.5%) and 64.0 gy(RBE) (N = 15;45.5%) in 16 fractions.", "subitem_description_type": "Abstract"}]}, "item_8_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Inpact Journals"}]}, "item_8_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "10.18632/oncotarget.24390 ", "subitem_relation_type_select": "DOI"}}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": " 1949-2553", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Hayashi, Kazuhiko"}], "nameIdentifiers": [{"nameIdentifier": "491371", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Koto, Masashi"}], "nameIdentifiers": [{"nameIdentifier": "491372", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ikawa, Hiroaki"}], "nameIdentifiers": [{"nameIdentifier": "491373", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ogawa, Kazuhiko"}], "nameIdentifiers": [{"nameIdentifier": "491374", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kamada, Tadashi"}], "nameIdentifiers": [{"nameIdentifier": "491375", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "林 和彦", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "491376", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "小藤 昌志", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "491377", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "伊川 裕明", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "491378", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "小川 和彦", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "491379", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "鎌田 正", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "491380", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": " Efficacy and safety of carbon-ion radiotherapy for lacrimal gland carcinomas with extraorbital extension: a retrospective cohort study", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": " Efficacy and safety of carbon-ion radiotherapy for lacrimal gland carcinomas with extraorbital extension: a retrospective cohort study"}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/48793", "pubdate": {"attribute_name": "公開日", "attribute_value": "2018-04-23"}, "publish_date": "2018-04-23", "publish_status": "0", "recid": "48793", "relation": {}, "relation_version_is_last": true, "title": [" Efficacy and safety of carbon-ion radiotherapy for lacrimal gland carcinomas with extraorbital extension: a retrospective cohort study"], "weko_shared_id": -1}
Efficacy and safety of carbon-ion radiotherapy for lacrimal gland carcinomas with extraorbital extension: a retrospective cohort study
https://repo.qst.go.jp/records/48793
https://repo.qst.go.jp/records/487931c835fc8-d08c-4cdb-b5c1-e695cb8f502e
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2018-04-23 | |||||
タイトル | ||||||
タイトル | Efficacy and safety of carbon-ion radiotherapy for lacrimal gland carcinomas with extraorbital extension: a retrospective cohort study | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Hayashi, Kazuhiko
× Hayashi, Kazuhiko× Koto, Masashi× Ikawa, Hiroaki× Ogawa, Kazuhiko× Kamada, Tadashi× 林 和彦× 小藤 昌志× 伊川 裕明× 小川 和彦× 鎌田 正 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Purpose: To evaluate the efficacy and safety of carbon-ion radiotherapy (CIRT) for patients with lacrimal gland carcionmas (LGCs) with extraorbital extension Results: The median follow-up period was 53.7 months. The 5-year local control and overall survival rates were 62% and 65%, respectively. Regarding late toxicities, 12 patients (36.4%) developed Grade 4 optic nerve disorders, including visual losses of the disweased side (N = 8;66.7%), and 1 patient (3.0%) developed a Grade 3 optic nerve disorder. Three patients (9.0%) developed Grade 3 cataracts, 3 (9.0%) developed glaucoma, and 1 (3.0%) developed retinopathy. Two patients (6.1%) had Grade 4 central nervous system necrosis. No Grade 5 late toxicities were observed. The 5-year preservation rate of the ipsilateral eyeball was 86%. Conclusion: Definitive CIRT is effective for LGCs with extraorbital extension with acceptable toxicity. Methods: Thirty-three patients treated with CIRT at our institution were analyzed. Sixteen patients (48.5%) had adenoid cystic carcinoma, 8 (24.2%) had adnocarcinoma not otherwise specified, and 9 (27.3%) had other types of the disease. Thirty patients (90.9%) had T4c tumors. the prescribed doses were 57.6 Gy (relative biological effectiveness [RBE]) (N = 18; 54.5%) and 64.0 gy(RBE) (N = 15;45.5%) in 16 fractions. |
|||||
書誌情報 |
Oncotarget 巻 9, 号 16, p. 12932-12940, 発行日 2018-02 |
|||||
出版者 | ||||||
出版者 | Inpact Journals | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1949-2553 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.18632/oncotarget.24390 |