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Feeding period of selenium-deficient diet and response of redox relating minerals
https://repo.qst.go.jp/records/48500
https://repo.qst.go.jp/records/485002281bbe4-46e7-404a-9bd0-0c33e636cb8a
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-07-23 | |||||
タイトル | ||||||
タイトル | Feeding period of selenium-deficient diet and response of redox relating minerals | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Ken-ichiro, Matsumoto
× Ken-ichiro, Matsumoto× Ariyoshi, Marie× Terada, Sachiyo× Okajo, Aya× Urata, Hiromi× Sakuma, Yasunobu× Satoh, Kazue× Ushio, Fusao× Tsukada, Masamichi× Endo, Kazutoyo× Kenichiro, Matsumoto |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Dynamics of redox relating biotrace elements, selenium (Se), iron (Fe), and zinc (Zn) in liver, kidney, and spleen of selenium deficient Wistar male rats in a series of feeding period (from 0 to 8 weeks) were studied using instrumental neutron activation analysis (INAA). AST, ALT, and BUN for the plasma fraction of the rat bloods and the concentration of vitamin C and vitamin E in the liver homogenates were measured. The initial purpose of this study was to find Fe and Zn as sensitive indices of the tissue oxidative stress levels. However, the relationships among the biotrace elements and the oxidative stress/injury were much complicated. Control group, which was fed Se-deficient diet with Na2SeO4 (0.1 mg selenium/L) in drinking water, showed strange response of Se and Zn contents in the kidney and showed high BUN. Supplementation of inorganic Se by biased Se source may serve as another source of a stress especially in the kidney. The Fe and Zn contents in the liver and kidney look sensitive to the Se-deficiency and/or relating oxidative stresses. Short term exposure to the Se-deficiency appeared to consume Fe and Zn in the liver and kidney. In contrast, long term or chronic exposure to Se-deficiency appeared to accumulate Fe and Zn in liver and kidney. | |||||
書誌情報 |
Journal of Health Science (Tokyo, Japan) 巻 52, 号 6, p. 694-702, 発行日 2006-12 |
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出版者 | ||||||
出版者 | Pharmaceutical Society of Japan | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1344-9702 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1248/jhs.52.694 | |||||
関連サイト | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1248/jhs.52.694 |