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Multi-institutional retrospective study of mucoepidermoid carcinoma treated with carbon-ion radiotherapy.
https://repo.qst.go.jp/records/48358
https://repo.qst.go.jp/records/483580f133292-2c23-40c6-b350-936544f68ad9
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-11-02 | |||||
| タイトル | ||||||
| タイトル | Multi-institutional retrospective study of mucoepidermoid carcinoma treated with carbon-ion radiotherapy. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Shirai, Katsuyuki
× Shirai, Katsuyuki× Koto, Masashi× Demizu, Yuusuke× Suefuji, Hiroaki× Ohno, Tatsuya× Tsuji, Hiroshi× Okimoto, Tomoaki× Shioyama, Yoshiyuki× Saitou, Jyunnichi× Nemoto, Kenji× Nakano, Takashi× Kamada, Tadashi× 白井 克幸× 小藤 昌志× 出水 祐介× 末藤 大明× 大野 達也× 辻 比呂志× 沖本 智昭× 塩山 善之× 齋藤 淳一× 根本 建二× 中野 隆史× 鎌田 正 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Abstract \nThis study aimed to evaluate the clinical outcomes of patients with mucoepidermoid carcinomas in the head and neck treated with carbon-ion radiotherapy. Data from 26 patients who underwent carbon-ion radiotherapy in four facilities were analyzed in this multi-institutional retrospective study: the Japan Carbon-ion Radiation Oncology Study Group. The median follow-up time was 34 months. One patient experienced local recurrence, and the 3-year local control rate was 95%. One patient developed lymph node recurrence and five developed distant metastases. The 3-year progression-free survival rate was 73%. Five patients died, two of mucoepidermoid carcinoma and three of intercurrent disease. The 3-year overall survival rate was 89%. Acute mucositis and dermatitis of grade 3 or higher were experienced by 19% and 8% of patients, respectively; these improved with conservative therapy. Late mucositis and osteonecrosis of jaw were observed in 12% and 23% of patients, respectively. The 3-year cumulative rate of any late adverse event of grade 3 or higher was 14%. None of the patients died of the acute or late adverse events. Carbon-ion radiotherapy was efficacious and safe for treating mucoepidermoid carcinoma in this multi-institutional retrospective study (registration no. UMIN000024473). We are currently undertaking a prospective multicenter study. |
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| 書誌情報 |
Cancer Science 巻 108, 号 7, p. 1447-1451, 発行日 2017-07 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1347-9032 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 28474791 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1111/cas.13270 | |||||
