WEKO3
アイテム
67Cu-Radiolabeling of a multimeric RGD peptide for αVβ3 integrin-targeted radionuclide therapy: stability, therapeutic efficacy, and safety studies in mice.
https://repo.qst.go.jp/records/47700
https://repo.qst.go.jp/records/47700d5bddc9c-ee45-4ede-857f-5754f2e564de
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-04-12 | |||||
| タイトル | ||||||
| タイトル | 67Cu-Radiolabeling of a multimeric RGD peptide for αVβ3 integrin-targeted radionuclide therapy: stability, therapeutic efficacy, and safety studies in mice. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Jin, Zhao-Hui
× Jin, Zhao-Hui× Furukawa, Takako× Ohya, Tomoyuki× Degardin, Mélissa× Sugyo, Aya× B, Tsuji Atsushi× Fujibayashi, Yasuhisa× Zhang, Ming-Rong× Higashi, Tatsuya× Boturyn, Didier× Dumy, Pascal× Saga, Tsuneo× 金 朝暉× 古川 高子× 大矢 智幸× 須尭 綾× 辻 厚至× 藤林 康久× 張 明栄× 東 達也× 佐賀 恒夫 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Copper-67 (Cu) is one of the most promising radionuclides for internal radiation therapy. Globally, several projects have recently been initiated for developing innovative approaches for the large-scale production of Cu. Encouraged by these, we performed Cu-radiolabeling of a tetrameric cyclic Arg-Gly-Asp (cRGD) peptide conjugate, cyclam-RAFT-c(-RGDfK-)4, which selectively targets αVβ3 integrin (αVβ3), the transmembrane receptor involved in tumor invasion, angiogenesis, and metastasis. We also evaluated the therapeutic potential and safety of this radiocompound. | |||||
| 書誌情報 |
Nuclear medicine communications 巻 38, 号 4, p. 347-355, 発行日 2017-03 |
|||||
| 出版者 | ||||||
| 出版者 | Lippincott Williams & Wilkins | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0143-3636 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 28291159 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1097/MNM.0000000000000646 | |||||
