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Dependence of the bystander effect for micronucleous formation on dose of heavy-ion radiation in normal human fibrobrasts
https://repo.qst.go.jp/records/47371
https://repo.qst.go.jp/records/4737100de699d-4fbc-4596-a723-c2e1709984c8
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-01-18 | |||||
| タイトル | ||||||
| タイトル | Dependence of the bystander effect for micronucleous formation on dose of heavy-ion radiation in normal human fibrobrasts | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Matsumoto, Yoshitaka
× Matsumoto, Yoshitaka× Hamada, Nobuyuki× Aoki-Nakano, Mizuho× Funayama, Tomoo× Sakashita, Tetsuya× Wada, Seiichi× Kakizaki, Takehiko× Kobayashi, Yasuhiko× 古澤, 佳也× 古澤 佳也 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Ionising radiation-induced bystander effects are well recognised, but its dependence on dose or linear energy transfer (LET) is still a matter of debate. To test this, 49 sites in confluent cultures of AG01522D normal human fibroblasts were targeted with microbeams of carbon (103 keV mm21), neon (375 keV mm21) and argon ions (1260 keV mm21) and evaluated for the bystander-induced formation of micronucleus that is a kind of a chromosome aberration. Targeted exposure to neon and argon ions significantly increased the micronucleus frequency in bystander cells to the similar extent irrespective of the particle numbers per site of 1–6. In contrast, the bystander micronucleus frequency increased with increasing the number of carbon-ion particles in a range between 1 and 3 particles per site and was similar in a range between 3 and 8 particles per site. These results suggest that the bystander effect of heavy ions for micronucleus formation depends on dose. | |||||
| 書誌情報 |
Radiation Protection Dosimetry 巻 166, 号 1-4, p. 152-156, 発行日 2015-08 |
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| 出版者 | ||||||
| 出版者 | Oxford University Press. | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0144-8420 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 26242975 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | doi:10.1093/rpd/ncv177 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://rpd.oxfordjournals.org/content/166/1-4/152.long | |||||
| 関連名称 | http://rpd.oxfordjournals.org/content/166/1-4/152.long | |||||
