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Particle radiotherapy for prostate cancer.
https://repo.qst.go.jp/records/47171
https://repo.qst.go.jp/records/47171b4c64f17-5bee-488a-b3ed-184ed14a57de
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2015-07-22 | |||||
タイトル | ||||||
タイトル | Particle radiotherapy for prostate cancer. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Shioyama, Yoshiyuki
× Shioyama, Yoshiyuki× Tsuji, Hiroshi× Suefuji, Hiroaki× Sinoto, Makoto× Matsunobu, Akira× Toyama, Shingo× Nakamura, Katsumasa× Kudo, Sho× 辻 比呂志 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Recent advances in external beam radiotherapy have allowed us to deliver higher doses to the tumors while decreasing doses to the surrounding tissues. Dose escalation using high-precision radiotherapy has improved the treatment outcomes of prostate cancer. Intensity-modulated radiation therapy has been widely used throughout the world as the most advanced form of photon radiotherapy. In contrast, particle radiotherapy has also been under development, and has been used as an effective and non-invasive radiation modality for prostate and other cancers. Among the particles used in such treatments, protons and carbon ions have the physical advantage that the dose can be focused on the tumor with only minimal exposure of the surrounding normal tissues. Furthermore, carbon ions also have radiobiological advantages that include higher killing effects on intrinsic radio-resistant tumors, hypoxic tumor cells and tumor cells in the G0 or S phase. However, the degree of clinical benefit derived from these theoretical advantages in the treatment of prostate cancer has not been adequately determined. The present article reviews the available literature on the use of particle radiotherapy for prostate cancer as well as the literature on the physical and radiobiological properties of this treatment, and discusses the role and the relative merits of particle radiotherapy compared with current photon-based radiotherapy, with a focus on proton beam therapy and carbon ion radiotherapy. | |||||
書誌情報 |
International journal of urology : official journal of the Japanese Urological Association 巻 22, 号 1, p. 33-39, 発行日 2014-10 |
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出版者 | ||||||
出版者 | Blackwell Science Asia | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0919-8172 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 25308767 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1111/iju.12640 |