WEKO3
アイテム
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Old but new methods in radiation oncology: hyperbaric oxygen therapy.
https://repo.qst.go.jp/records/46952
https://repo.qst.go.jp/records/46952ef50757d-0751-46b6-a20d-d7ff3ac8ef53
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-11-18 | |||||
タイトル | ||||||
タイトル | Old but new methods in radiation oncology: hyperbaric oxygen therapy. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Ogawa, Kazuhiko
× Ogawa, Kazuhiko× Kohshi, Kiyotaka× Ishiuchi, Syogo× Matsushita, Masayuki× Yoshimi, Naoki× Murayama, Sadayuki× 吉見 直己 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The presence of hypoxic tumor cells is widely regarded as one of the main reasons behind the failure to control malignant tumors with radiotherapy treatments. Since hyperbaric oxygenation (HBO) improves the oxygen supply to the hypoxic tumor cells, HBO therapy has previously been used in combination with simultaneous radiotherapy to treat malignant tumors. In some clinical trials, significant improvements in local control and survival have been seen in cancers of the head and neck and the uterine cervix. However, the delivery of simultaneous HBO therapy and radiotherapy is both complex and time-consuming, with some trials reporting increased side effects. As a result, the regimen of HBO therapy in combination with simultaneous radiotherapy has yet to be used as a standard treatment for malignant tumors. In recent years, however, radiotherapy immediately after HBO therapy has been emerging as an attractive approach for overcoming hypoxia in cancer treatment. Several studies have reported that radiotherapy immediately after HBO therapy was safe and seemed to be effective in patients with high-grade gliomas. Also, this approach may protect normal tissues from radiation injury. To accurately estimate whether the delivery of radiotherapy immediately after HBO therapy can be beneficial in patients with high-grade gliomas and other cancers, further prospective studies are warranted. | |||||
書誌情報 |
International Journal of Clinical Oncology 巻 18, 号 3, p. 364-370, 発行日 2013-06 |
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出版者 | ||||||
出版者 | Springer-Verlag Tokyo | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1341-9625 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 23463521 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s10147-013-0537-6 |